Evidence map›Paper›PMID 41266558›Full record

ArticleScientific reports2025

Impact of post stroke fatigue on saccadic eye movement control and learning through inflammatory mechanisms.

Akram Jamali, Tourandokht Baluchnejadmojarad, Hajar Mehdizadeh, Seyede Zohreh Jazaeri, Soheila Fallah, Ghorban Taghizadeh

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Akram JamaliDepartment of Neurosciences, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran.
Tourandokht BaluchnejadmojaradDepartment of Physiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Hajar MehdizadehIndependent Researcher, Shiraz, Iran.
Seyede Zohreh JazaeriDepartment of Neurosciences, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran.
Soheila FallahDepartment of Neurosciences, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran.
Ghorban TaghizadehDepartment of Occupational Therapy, Geriatric Mental Health Research Center, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran. taghizadeh.gh@iums.ac.ir.ORCID http://orcid.org/0000-0002-0145-9599

Funding

Iran University of Medical Sciences 26242
6 · The paper itself

Abstract

This study aimed to (1) examine the impact of post-stroke fatigue (PSF) on saccadic control, (2) assess the effect of PSF on saccade adaptation, and (3) explore the correlation between serum levels of interleukin-6 (IL-6) and high-sensitivity C-reactive protein (hsCRP) with saccade control and adaptation in chronic stroke survivors. Fatigue was assessed in stroke survivors with high fatigue (HF-stroke, n = 13) and low fatigue (LF-stroke, n = 13) using the Fatigue Severity Scale and Fatigue Assessment Scale, alongside age-matched healthy controls (n = 13). The stroke groups were compared based on lesion volume and location. Eye-tracking recorded pro-saccade, anti-saccade, and saccade adaptation parameters. Serum levels of IL-6 and hsCRP were measured. HF-stroke survivors demonstrated significantly higher saccade latency, duration, and positional error, along with lower velocity, amplitude, and gain in pro- and anti-saccade tasks compared to the LF-stroke group (p < 0.05). HF-stroke survivors showed a lower adaptation rate (F

Indexed as

FatigueInflammationSaccadesStrokeAdaptation, PhysiologicalAgedCase-Control StudiesC-Reactive ProteinFemaleHumansInterleukin-6MaleMiddle AgedC-Reactive ProteinInterleukin-6InflammationMotor controlMotor learningPSFSaccadeStroke

Identifiers

PMID41266558
PMCPMC12635319

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.