Evidence map›Paper›PMID 41266501›Full record

ArticleScientific reports2025

Development of a novel method to evaluate gingivitis in children by combining rapid saliva test systems.

Yuko Iwamoto, Chieko Mitsuhata, Shunya Ikeda, Yuya Ito, Shuma Hamaguchi, Eimi Tabata, Yasuko Tsuge, Ami Kaneki, Masashi Ogawa, Taku Nishimura and 6 more

Abstract read
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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yuko IwamotoDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Chieko MitsuhataDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Shunya IkedaDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Yuya ItoDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Shuma HamaguchiDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Eimi TabataDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Yasuko TsugeDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Ami KanekiDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Masashi OgawaDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Taku NishimuraDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Mariko KametaniDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Satoru KusakaDepartment of Pediatric Dentistry, Hiroshima University Hospital, Hiroshima, Japan.
Yuria AsaoDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Tatsuya AkitomoDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Katsuyuki KozaiDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan.
Ryota NomuraDepartment of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, -2-3 Kasumi, Minami-Ku, Hiroshima, 734-8553, Japan. rnomura@hiroshima-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few tools can objectively assess the risk of gingivitis in children. We developed a novel method to evaluate gingivitis by combining rapid saliva test systems. Seventy-six subjects (aged 3-19 years) were included in the study. Gingival condition was evaluated using the papillary marginal attached (PMA) index. Liquid gargled by the subjects was examined using Perioscreen to measure the amount of hemoglobin, and the Salivary Multi Test (SMT) to quantify six factors related to oral health. PMA values were significantly higher in subjects with positive hemoglobin than in those with negative hemoglobin (P < 0.001). Of the six SMT items, buffering capacity and protein showed correlations with PMA value (R

Indexed as

GingivitisSalivaAdolescentChildChild, PreschoolFemaleHemoglobinsHumansMaleROC CurveYoung AdultHemoglobins

Identifiers

PMID41266501
PMCPMC12635276

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.