Evidence map›Paper›PMID 41265879›Full record

Trial reportThe Journal of international medical research2025

Effectiveness and safety of a lower-limb walking assist device for motor function recovery in subacute stroke patients: A prospective, randomized, open, parallel-controlled, noninferiority study.

Bing Xiong, Xinyuan Wang, Xin Xu, Zhilai Lou, Ting Tong, Danlei Gu, Kedan Zhang, Huanhuan Liu

Abstract readRandomized Controlled TrialEquivalence Trial
In one paragraph

Trial report in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bing XiongThe Second Affiliated Hospital of Zhejiang University, China.ORCID 0000-0002-9249-3388
Xinyuan WangThe Second Affiliated Hospital of Zhejiang University, China.ORCID 0009-0003-2027-9678
Xin XuThe Second Affiliated Hospital of Zhejiang University, China.
Zhilai LouThe Second Affiliated Hospital of Zhejiang University, China.
Ting TongThe Second Affiliated Hospital of Zhejiang University, China.
Danlei GuThe Second Affiliated Hospital of Zhejiang University, China.
Kedan ZhangThe Second Affiliated Hospital of Zhejiang University, China.
Huanhuan LiuThe Second Affiliated Hospital of Zhejiang University, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveTo evaluate the effectiveness and safety of the MI-R1 lower-limb walking assist device for gait training in subacute stroke patients.MethodsThe experimental group received lower-limb function training using the lower-limb training device. In contrast, the control group received lower-limb function training provided by a therapist. After 4 weeks, the patients were evaluated for certain indicators. The primary outcome was the Fugl-Meyer Assessment Lower Extremity score on day 28 (±7 days). The secondary outcomes included the Functional Ambulation Category score, Modified Barthel Index score, safety indicators, and incidence of adverse events.ResultsAfter treatment, the noninferiority statistic between the experimental and control groups was -0.1976 (-1.5051, 1.1099). The lower limit of the 95% confidence interval was greater than the noninferiority margin. There was no significant difference in the Functional Ambulation Category or Modified Barthel Index scores between the experimental and control groups at 0, 14, and 28 days (

Indexed as

Lower ExtremityRecovery of FunctionStrokeStroke RehabilitationWalkingAgedFemaleHumansMaleMiddle AgedProspective StudiesTreatment Outcomelower limbmotor functionStrokewalkingwalking device

Identifiers

PMID41265879
PMCPMC12639206

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.