Evidence map›Paper›PMID 41265167›Full record

ArticleInternational dental journal2026

Assessing Sealing Ability of C-Root SP Strontium Silicate Sealer With Different Obturation Techniques: An in vitro Study.

Suixin Hu, Jianshe Li, Meng Xu, Laiqing Xu, Yangming Yin, Peng Xue, Liping Dong, Lin Wang, Huixia He, Ying Liu and 2 more

Abstract read
In one paragraph

Article in International dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Suixin HuDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Jianshe LiOutpatient Department of TPL, Southern Medical Branch of PLA General Hospital, Beijing, China.
Meng XuDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Laiqing XuDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Yangming YinDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Peng XueDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Liping DongDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Lin WangDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Huixia HeDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Ying LiuDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, China. Electronic address: 1051167375@qq.com.
Qiang LuoDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, China. Electronic address: pkuhawking@foxmail.com.
Fei ChenDepartment of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, China. Electronic address: czjch1209@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate sealing ability of C-Root SP strontium silicate sealer combined with 3 different obturation techniques in the root canal treatment of single-canal teeth.

methods192 human single-canal permanent teeth were decoronated at the cementoenamel junction to standardize 10 mm length, which were then randomly divided into 4 groups (n = 43/group): Group A (C-Root SP+single-cone technique, SC), Group B (C-Root SP+warm vertical condensation, WVC), Group C (C-Root SP+cold lateral condensation, CLC) and Group D (iRoot SP+SC, as control), with additional positive/negative controls (n = 10 each). Following root canal preparation and technique-specific obturation with bioceramic sealers and gutta-percha, the samples were incubated (7 days, 37°C, 100% humidity) for sealer setting. Assessment techniques included micro-CT based void quantification in the apical (0-3.5 mm), middle (3.5-7 mm) and coronal (7-10.5 mm) regions (n = 5/group); SEM of material‒dentin interfaces (n = 3/group); dye penetration via 7-day 1% methylene blue immersion with stereomicroscopic leakage measurement (n = 20/group); and 28-day glucose leakage monitoring with spectrophotometric analysis (n = 15/group).

resultsMicro-CT revealed no significant differences in void volume between groups across all regions (P > .05). SEM showed minimal gaps only in Group C (CLC), with good adaptation in other groups. Dye leakage was similarly low in all experimental and control groups (A: 0.58 ± 0.10 mm; B: 0.62 ± 0.11 mm; C: 0.62 ± 0.10 mm; D: 0.60 ± 0.13 mm), significantly less than positive controls (5.99 ± 0.32 mm; P < .05). Glucose leakage increased over time but remained significantly lower than in positive controls, with no statistically significant differences observed among the experimental and control groups.

conclusionC-Root SP demonstrated a sealing ability equivalent to that of iRoot SP across all the tested obturation techniques (SC, WVC and CLC), indicating that the substitution of components (strontium silicate for calcium silicate) does not compromise performance. However, these in vitro findings do not reflect long-term sealing performance, further in vivo studies and prolonged evaluations are still warranted.

Indexed as

Dental BondingDental LeakageRoot Canal Filling MaterialsRoot Canal ObturationSilicatesGutta-PerchaHumansIn Vitro TechniquesMaterials TestingStrontiumX-Ray MicrotomographyGutta-PerchaRoot Canal Filling MaterialsSilicatesStrontiumBioceramic-based sealersMicro-leakage modelObturation techniqueSealing ability

Identifiers

PMID41265167
PMCPMC12666820

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.