Evidence map›Paper›PMID 41264561›Full record

ArticleExperimental physiology2026

How do physiological networks respond to normobaric hypoxia and isometric exercise?

Danilo Bondi, Cecilia Morandotti, Salvatore Annarumma, Carmen Santangelo, Tiziana Pietrangelo, Stefania Fulle, Vittore Verratti

Abstract read
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Decrypting network physiology for clinical practice.Frontiers in network physiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Danilo BondiDepartment of Neuroscience, Imaging and Clinical Sciences, University 'G. d'Annunzio' Chieti-Pescara, Chieti, Italy.ORCID https://orcid.org/0000-0003-1911-3606
Cecilia MorandottiNetwork Physiology Laboratory, UCL Division of Medicine, University College London, London, UK.
Salvatore AnnarummaDepartment of Neuroscience, Imaging and Clinical Sciences, University 'G. d'Annunzio' Chieti-Pescara, Chieti, Italy.ORCID https://orcid.org/0009-0006-6926-2131
Carmen SantangeloDepartment of Neuroscience, Imaging and Clinical Sciences, University 'G. d'Annunzio' Chieti-Pescara, Chieti, Italy.
Tiziana PietrangeloDepartment of Neuroscience, Imaging and Clinical Sciences, University 'G. d'Annunzio' Chieti-Pescara, Chieti, Italy.
Stefania FulleDepartment of Neuroscience, Imaging and Clinical Sciences, University 'G. d'Annunzio' Chieti-Pescara, Chieti, Italy.
Vittore VerrattiDepartment of Science, University 'G. d'Annunzio' Chieti-Pescara, Chieti, Italy.ORCID https://orcid.org/0000-0001-8343-9024

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dynamics of physiological systems are impacted by both exercise and hypoxia. Network models can be used to map the interactions between various physiological components in environmental physiology and exercise using the concepts of information theory. This cross-over study compared three normobaric conditions: control, simulated altitude of 2500 m (fraction of inspired oxygen:

Indexed as

ExerciseHypoxiaIsometric ContractionAdultAltitudeCross-Over StudiesFemaleHumansMaleOxygen ConsumptionYoung Adulthypoxic stress testinformation theorynetwork comparisonnetwork mappingnetwork physiologytransfer entropy

Identifiers

PMID41264561
PMCPMC13140655

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.