Evidence map›Paper›PMID 41264402›Full record

SynthesisCancer medicine2025

A Systematic Review on Machine Learning Techniques for Survival Analysis in Cancer.

Autumn O'Donnell, Michael Cronin, Shirin Moghaddam, Eric Wolsztynski

Abstract readSystematic Review
In one paragraph

Synthesis in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Autumn O'DonnellSchool of Mathematical and Statistical Sciences, University of Galway, Galway, Ireland.ORCID https://orcid.org/0000-0002-4787-7462
Michael CroninSchool of Mathematical Sciences, University College Cork, Cork, Ireland.
Shirin MoghaddamInsight SFI Centre for Data Analytics, Dublin, Ireland.ORCID https://orcid.org/0000-0002-9965-1510
Eric WolsztynskiInsight SFI Centre for Data Analytics, Dublin, Ireland.ORCID https://orcid.org/0000-0001-9770-9769

Funding

Higher Education AuthorityScience Foundation Ireland 12/RC/2289-P2
6 · The paper itself

Abstract

backgroundMachine learning (ML) offers opportunities to overcome limitations of conventional survival analyses, which are commonly found in cancer studies. However, the choice and levels of performance of ML methods vary across studies. As a result, it is unclear whether they consistently outperform traditional statistical methods and whether one particular ML strategy may outperform others for survival analysis. The present study aimed to systematically review the literature around this emerging topic.

methodsThis systematic review was conducted using the PRISMA guidelines. Electronic databases were systematically searched using keywords related to Machine Learning, Survival Analysis and Cancer. RESULTS &

conclusionThe review included 196 studies, from which 39 comparable studies were used for the analysis. Improved predictive performance was seen from the use of ML in almost all cancer types. Predictive performance of the different ML methods varied across cancer types, and multi-task and deep learning methods appeared to yield superior performance; however, it was reported in only a minority of papers. This study also highlighted great variability in both methodologies and their implementations.

Indexed as

Machine LearningNeoplasmsHumansSurvival Analysiscancermachine learningsurvival analysissystematic review

Identifiers

PMID41264402
PMCPMC12633653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.