Evidence map›Paper›PMID 41264361›Full record

ArticleJournal of adolescent and young adult oncology2026

Implementing a User-Centered Design to Develop a Web-Based Sperm Banking Decision Tool for Adolescent Males with Cancer.

Megan M Griffith, Emre Sezgin, Tanvi Karkare, Charleen I Roche, Jennifer English, Anthony Audino, Kathleen E Montgomery, Amanda J Saraf, Gwendolyn P Quinn, Ashley J Housten and 3 more

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Article in Journal of adolescent and young adult oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Megan M GriffithThe Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Emre SezginThe Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Tanvi KarkareThe Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Charleen I RocheThe Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Jennifer EnglishDivision of Hematology/Oncology/BMT, Nationwide Children's Hospital, Columbus, Ohio, USA.
Anthony AudinoDepartment of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, USA.
Kathleen E MontgomerySchool of Nursing, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Amanda J SarafDivision of Hematology Oncology and Stem Cell Transplant, Riley Hospital for Children, Indianapolis, Indiana, USA.
Gwendolyn P QuinnObstetrics and Gynecology, New York University Grossman School of Medicine, New York, New York, USA.
Ashley J HoustenDepartment of Surgery, Division of Public Health Sciences, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Michael SchererWorth the Wait Charity, Westerville, Ohio, USA.
Megan SchererWorth the Wait Charity, Westerville, Ohio, USA.
Leena NahataThe Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.

Funding

Adaptation and implementation of a web-based Family centered Adolescent Sperm banking decision Tool for adolescent males with cancerR01CA284073 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI Leena Nahata · 2023 to 2026
$1.4M
NCI NIH HHS R01 CA284073
6 · The paper itself

Abstract

purposeApproximately half of male childhood cancer survivors experience treatment-related fertility impairment. Regrets about missed sperm banking opportunities have been reported, yet few decision tools for male adolescents with cancer exist. This study aims to report the development, testing, and adaptation of the Family-centered Adolescent Sperm banking values clarification Tool (FAST) using an iterative, user-centered design with male adolescents with cancer and their caregivers and to obtain feedback from clinicians and community partners.

methodsMales (12-25 years, diagnosed with cancer in the past year, received a routine fertility consult where sperm banking was offered) and caregivers completed the FAST on a screen-recorded device, a semi-structured interview, the System Usability Scale (SUS), and a sociodemographic questionnaire. Feedback informed FAST adaptations and was documented using the Framework for Reporting Adaptations and Modifications-Expanded. Descriptive statistics and thematic analysis characterized FAST completion information.

resultsTen families (16 caregivers, 9 adolescents) enrolled. Themes included: ease of navigation, perceived usefulness of the FAST, and perspectives on tool adaptations. Forty-three FAST adaptations were made in response to participant feedback. Median FAST completion time was 5 minutes and 37 seconds. The mean FAST SUS score was high at 84.60 (minimum = 57.50, maximum = 100, standard deviation = 11.08).

conclusionsApplying an iterative, user-centered approach, the FAST was developed, usability-tested, and adapted to a web-based format that families found easy to navigate and useful. Web-based tools, such as the FAST, could improve the sperm banking decision-making process for adolescent males and their caregivers by addressing unmet needs and ultimately improving satisfaction with fertility counseling outcomes.

Indexed as

Decision MakingNeoplasmsSperm BanksUser-Centered DesignAdolescentAdultChildHumansInternetMaleYoung Adultadolescent cancerdigital healthsperm bankingusability testinguser-centered design

Identifiers

PMID41264361
PMCPMC13244301

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