Evidence map›Paper›PMID 41264249›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Joubert syndrome 26 protein enforces compartmentalized motility of a ciliary kinesin.

Shimin Wang, Ming Li, Guanghan Chen, Zhe Chen, Kexin Lei, Zeynep Ökten, Shanshan Xie, Tianhua Zhou, Wei Li, Guangshuo Ou

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shimin WangTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.ORCID 0009-0003-1841-6901
Ming LiTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.ORCID 0000-0003-4137-5290
Guanghan ChenTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.ORCID 0009-0009-7286-0759
Zhe ChenTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.ORCID 0009-0002-8988-6225
Kexin LeiTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.ORCID 0000-0003-1273-8849
Zeynep ÖktenPhysik Department E22, Technische Universitat Munchen, Garching 85748, Germany.ORCID 0000-0002-3848-3488
Shanshan XieChildren's Hospital, National Clinical Research Center for Child Health, Zhejiang University School of Medicine, Hangzhou 310052, China.ORCID 0000-0003-4294-8169
Tianhua ZhouDepartment of Cell Biology, Zhejiang University School of Medicine, Hangzhou 310058, China.
Wei LiSchool of Basic Medical Sciences, Tsinghua University, Beijing 100084, China.ORCID 0000-0001-9133-461X
Guangshuo OuTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.ORCID 0000-0003-1512-7824

Funding

MOST | National Key Research and Development Program of China (NKPs) 2019YFA0508401MOST | National Key Research and Development Program of China (NKPs) 2022YFA1302700MOST | National Key Research and Development Program of China (NKPs) 2024YFA1307301MOST | National Natural Science Foundation of China (NSFC) 31991190MOST | National Natural Science Foundation of China (NSFC) 32070706MOST | National Natural Science Foundation of China (NSFC) 32270773MOST | National Natural Science Foundation of China (NSFC) 32470730MOST | National Natural Science Foundation of China (NSFC) 92254306
6 · The paper itself

Abstract

Cilia are essential cellular antennae that rely on precise motor-driven transport to assemble and function. Two kinesin-2 motors-kinesin-II and OSM-3 in

Indexed as

Caenorhabditis elegans ProteinsCiliaEye AbnormalitiesKidney Diseases, CysticKinesinsRetinaAbnormalities, MultipleAnimalsCaenorhabditis elegansCerebellumHumansMicrotubulesCaenorhabditis elegans Proteinskinesin-IIKinesinsOSM-3 protein, C elegansciliaintraflagellar transport (IFT)Joubert syndromekinesin-2kinesin handover

Identifiers

PMID41264249
PMCPMC12663925

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.