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ArticleEuropean geriatric medicine2025

Lumbar puncture seems to be safe and practical ın oldest-old patients: a protocol from a memory center.

Mehmet Selman Ontan, Fatma Sena Dost, Derya Kaya, Esra Ates Bulut, Ali Ekrem Aydin, Acelya Gokdenız Yildirim, Ahmet Turan Isik

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Article in European geriatric medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Mehmet Selman OntanUnit for Aging Brain and Dementia, Department of Geriatric Medicine, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
Fatma Sena DostUnit for Aging Brain and Dementia, Department of Geriatric Medicine, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
Derya KayaUnit for Aging Brain and Dementia, Department of Geriatric Medicine, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
Esra Ates BulutDepartment of Geriatric Medicine, University of Health Sciences, Adana City Research and Training Hospital, Adana, Turkey.
Ali Ekrem AydinDepartment of Geriatric Medicine, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
Acelya Gokdenız YildirimUnit for Aging Brain and Dementia, Department of Geriatric Medicine, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
Ahmet Turan IsikUnit for Aging Brain and Dementia, Department of Geriatric Medicine, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey. atisik@yahoo.com.ORCID http://orcid.org/0000-0001-5867-6503

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePhysicians may hesitate to perform lumbar puncture (LP) with advancing age, particularly in daily practice in those aged 80 years or older. This study aimed to evaluate the characteristics and complications of LP in the oldest-old.

methodsThe medical records of all the patients who underwent LP in a geriatrics inpatient memory clinic were retrospectively reviewed with a specified protocol. As well as demographics, indication for LP, position during the procedure, the total number of LP attempts, the volume of CSF removed, post-LP headache (PLPH), and post-LP back pain at the LP site (PLPBP) were also obtained from the patients' files. The patients were divided into two groups based on their ages as older adults and oldest-old adults.

resultsIn this study, a total of 202 LPs were included, of which 39.6% were performed in those aged ≥ 80. PLPH was detected in 6.9% and PLPBP in 7.4% of all our patients, while the rates were 7.5% and 6.3% in the oldest-old group.The frequency of PLPH and PLPBP, the number of traumatic LP procedures, and repeated LP attempts were similar. between the groups. In regression analysis, only the medical history of headache was correlated with PLPH, as well as nonspecific headache, and intracranial hypotension. PLPBP was associated with the number of LP attempts (≥ 3).

conclusionIn the oldest old, lumbar puncture is as safe as in younger-older adults when it is performed in experienced geriatric clinics with the specified protocol.

Indexed as

Post-Dural Puncture HeadacheSpinal PunctureAgedAged, 80 and overAge FactorsFemaleHumansMaleRetrospective StudiesOldest oldPainPost-lumbar puncture headache

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.