ArticleNeurosurgical review2025
Prognostic value of perivascular spaces, diffusion tensor imaging-derived indices, and choroid plexus in idiopathic normal pressure hydrocephalus.
Article in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- MRI-based cerebrospinal fluid volumetric indices for predicting tap test response in idiopathic normal pressure hydrocephalus.Radiological physics and technology · 2026Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
This study investigated the ability of the perivascular space (PVS), free water in the white matter (FW-WM), diffusion tensor imaging analysis along the PVS (DTI-ALPS), and choroid plexus (CP) to predict postoperative prognosis for idiopathic normal pressure hydrocephalus (iNPH), and the relationships between these MRI indices and clinical phenotypes. This retrospective study included patients with iNPH who underwent magnetic resonance imaging (MRI). MRI indices included the PVS volume fraction (PVSVF), FW-WM fractional volume, DTI-ALPS, and CP volume fraction (CPVF). Predictors of improvement were analyzed using a logistic regression model and receiver operating characteristic analysis. The primary endpoint was the improvement in the modified Rankin Scale (mRS) score at 1 year after surgery; secondary endpoints were the iNPH grading scale (iNPHGS), Mini-Mental State Examination (MMSE), and Timed Up-and-Go (TUG) test at 1 year. Multiple comparisons were controlled using the false discovery rate (FDR). The 32 enrolled patients (70 ± 7 years) included 17 men. The improvement rates in mRS, iNPHGS, MMSE, and TUG were 56% (18/32), 59% (19/32), 60% (15/25), and 57% (12/21), respectively. No significant differences in the examined MRI indices or clinical symptoms were observed between improved and non-improved groups for either the primary or secondary outcomes (all p > 0.05). Lower DTI-ALPS scores were correlated with lower MMSE scores (r = 0.542, p
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Registered trials
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