ArticleSurgery today2026
Benefits and risks of simultaneous versus staged laparoscopic resection for colorectal cancer with synchronous liver metastases.
Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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9 authors.
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Abstract
purposeTo compare the advantages and disadvantages of simultaneous laparoscopic hepatocolorectal resection and staged resection for colorectal cancer with synchronous liver metastasis.
methodsPatients with colorectal cancer and synchronous liver metastases who underwent laparoscopic surgery were divided into simultaneous (n = 38) and staged (n = 56) resection groups and their short-term outcomes and medical expenses were then retrospectively compared.
resultsThe postoperative hospital stay was significantly shorter and the total medical costs were lower in the simultaneous group. However, the major complication rate (Clavien-Dindo classification ≥ 3a) was higher in the simultaneous group (28.9% vs. 12.5%, P = 0.047). After performing propensity score-adjusted logistic regression, simultaneous resection remained significantly associated with major complications (odds ratio, 5.11; P = 0.006). In a univariate analysis, the platelet count < 150,000/µL, liver metastasis diameter ≥ 3 cm, and difficulty score ≥ 6 were identified as potential risk factors for major complications in the simultaneous group. In a multivariate analysis, a difficulty score ≥ 6 was a significant risk factor (odds ratio, 9.63; P = 0.004).
conclusionsSimultaneous laparoscopic resection reduces the surgical burden and medical costs but carries a heightened perioperative risk. Staged resection should therefore be considered for patients with risk factors, particularly for those requiring hepatectomy with a difficulty score of ≥ 6.
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