Evidence map›Paper›PMID 41263740›Full record

ArticleJACC. Case reports2026

Recurrent Rheumatic Carditis Presenting With Severe Biventricular Dysfunction Despite a Normally Functioning Mechanical Mitral Valve.

José Victor da Nóbrega Borges, Samira Abdel Correia Leila

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

José Victor da Nóbrega BorgesFlorida International University and Baptist Health South Florida, Miami, Florida, USA. Electronic address: jdanobre@fiu.edu.
Samira Abdel Correia LeilaHospital Israelita Albert Einstein, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRheumatic heart disease (RHD) remains a major cause of cardiovascular morbidity in endemic regions. Recurrence of acute rheumatic fever (ARF) in adults, especially after valve surgery, is rare but clinically significant. CASE SUMMARY: A 44-year-old man with rheumatic mitral stenosis underwent mechanical mitral valve replacement. He presented 5 years later with dyspnea, orthopnea, and fatigue. Echocardiography showed new severe biventricular systolic dysfunction (left ventricular ejection fraction 20%) with preserved prosthetic function. Coronary computed tomography angiography excluded obstructive disease, and pulmonary embolism was ruled out. Elevated inflammatory markers raised suspicion for recurrent rheumatic carditis. He received anti-inflammatory therapy and guideline-directed medical therapy for heart failure, with progressive recovery. DISCUSSION: Recurrent ARF should remain a diagnostic consideration in adults with prior RHD and new ventricular dysfunction, even after valve replacement. TAKE-HOME MESSAGES: Recurrent ARF may occur post-surgery and cause myocardial dysfunction. Echocardiography and multimodality imaging are essential for diagnosis and management.

Indexed as

acute heart failuremitral valverheumatic heart disease

Identifiers

PMID41263740
PMCPMC12925962

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.