ArticleJACC. Case reports2026
First Reported Case of Infection Involving a Leadless Atrial Pacemaker.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Double trouble in device infection: Concomitant transvenous and leadless pacemaker infection.HeartRhythm case reports · 2026Article
- Leadless Pacemaker Infections: When Silver Bullets Are No Longer Immune.JACC. Case reports · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLeadless pacemakers were developed to reduce infection risk compared with transvenous systems. However, real-world data on device-related infections in newer models like the leadless atrial pacemaker (AVEIR AR) remain limited. CASE SUMMARY: A 70-year-old man with atrial fibrillation and prior methicillin-resistant Staphylococcus aureus (MRSA) pacemaker infection presented with acute respiratory failure and MRSA bacteremia 3 months after implantation of the leadless atrial pacemaker. Imaging showed a cystic mass attached to the device. The pacemaker was percutaneously extracted under intracardiac echocardiography guidance. Persistent bacteremia prompted aspiration of the residual mass using a percutaneous aspiration device (AlphaVac system). Cultures confirmed MRSA. DISCUSSION: This represents the first documented case of endocarditis involving a leadless atrial pacemaker system. Although leadless pacemakers are designed to minimize infection, they are not immune to serious complications. TAKE-HOME MESSAGES: Leadless pacemakers can still develop infections. Percutaneous aspiration-guided removal is a feasible management option. Prompt recognition and intervention are essential.
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Registered trials
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