Evidence map›Paper›PMID 41263662›Full record

ArticleRadiology. Cardiothoracic imaging2025

Cardiovascular MRI-based Biventricular Perfusion Assessment in Two Patients with Chronic Thromboembolic Pulmonary Hypertension Undergoing Pulmonary Thromboendarterectomy.

Lexiaozi Fan, María Davó-Jiménez, Brandon C Benefield, Nour Beydoun, David Dushfunian, Sebastian Cohn, Michael Cuttica, Ruben Mylvaganam, S Chris Malaisrie, Stephen Chiu and 10 more

Abstract readCase Reports
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Lexiaozi Fan *Department of Radiology, Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Ste 1600, Chicago, IL 60611.ORCID 0000-0002-3714-5372
María Davó-Jiménez *Department of Radiology, Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Ste 1600, Chicago, IL 60611.ORCID 0000-0002-7041-5039
Brandon C BenefieldDivision of Cardiology, Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Nour BeydounDivision of Cardiology, Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
David DushfunianDepartment of Radiology, Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Ste 1600, Chicago, IL 60611.ORCID 0000-0002-0628-1961
Sebastian CohnDepartment of Biomedical Engineering, Northwestern University, Evanston, Ill.ORCID 0000-0001-7819-8289
Michael CutticaDivision of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Ruben MylvaganamDivision of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
S Chris MalaisrieDivision of Cardiac Surgery, Northwestern University Feinberg School of Medicine, Chicago, Ill.ORCID 0000-0002-0704-0334
Stephen ChiuDivision of Cardiac Surgery, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Li-Yueh HsuDepartment of Radiology and Imaging Sciences, National Institutes of Health, Bethesda, Md.ORCID 0000-0002-0826-7290
Ryan AveryDepartment of Radiology, Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Ste 1600, Chicago, IL 60611.ORCID 0000-0002-7913-0574
Daniel SchimmelDivision of Cardiology, Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.ORCID 0000-0001-6035-7317
Yasmin RazaDivision of Cardiology, Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Jordyn DurkinDivision of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Donny NietoDepartment of Radiology, Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Ste 1600, Chicago, IL 60611.
Michael MarklDepartment of Radiology, Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Ste 1600, Chicago, IL 60611.ORCID 0000-0002-7686-1128
Daniel C LeeDivision of Cardiology, Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.ORCID 0000-0001-9447-4175
Daniel KimDepartment of Radiology, Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Ste 1600, Chicago, IL 60611.ORCID 0000-0003-2660-8973
Benjamin H FreedDivision of Cardiology, Department of Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.

Funding

Precision MRI of Left Atrial Fibrosis for Patients with Atrial FibrillationR01HL116895 · NHLBI · UNIVERSITY OF UTAH · PI KIM, DANIEL · 2014 to 2025
$5.1M
Wideband 3D LGE and Coronary MRA for Planning Ventricular Tachycardia AblationR01HL151079 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniel Kim, Daniel Ching-Hao Lee · 2020 to 2026
$4.0M
Classification and Prognostication in Pulmonary Thromboembolism Using Computed Tomography Image AnalyticsR01HL164717 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Farbod Nicholas Rahaghi · 2022 to 2026
$3.6M
Quantitative Detection of Coronary Microvascular Dysfunction in Long COVID Patients using a Comprehensive, Rapid, Free-Breathing Cardiovascular MRIR01HL167148 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniel Kim, Daniel Ching-Hao Lee · 2023 to 2026
$3.1M
Safe and Effective MRI for Pediatric Patients with a Cardiac Implantable Electronic DeviceR01HL168859 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Laleh Golestani Rad, Daniel Kim · 2024 to 2026
$2.0M
NHLBI NIH HHS R01 HL116895NHLBI NIH HHS R01 HL151079NHLBI NIH HHS R01 HL164717NHLBI NIH HHS R01 HL167148NHLBI NIH HHS R01 HL168859
6 · The paper itself

Abstract

Chronic thromboembolic pulmonary hypertension (CTEPH) can lead to right ventricular (RV) ischemia and dysfunction due to chronic pulmonary artery obstruction and increased afterload. While cardiovascular MRI (CMR) enables noninvasive assessment of myocardial perfusion, its role in CTEPH remains unclear. The authors report adenosine stress perfusion CMR findings from two patients with CTEPH before and after pulmonary thromboendarterectomy (PTE). Both showed reduced biventricular perfusion before PTE; one demonstrated post-PTE improvement. Perfusion findings aligned with invasive hemodynamics, suggesting that CMR-derived myocardial perfusion reserve may serve as a valuable tool for assessing treatment response and RV pathophysiologic characteristics in CTEPH.

Indexed as

EndarterectomyHypertension, PulmonaryMagnetic Resonance ImagingMyocardial Perfusion ImagingPulmonary EmbolismChronic DiseaseHeart VentriclesHumansPulmonary ArteryCardiacChronic Thromboembolic Pulmonary HypertensionMyocardial Blood FlowMyocardial Perfusion ReservePulmonary ArteriesPulmonary ThromboendarterectomyQuantitative Perfusion Cardiovascular MRI

Identifiers

PMID41263662
PMCPMC12728512

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.