Evidence map›Paper›PMID 41263561›Full record

ArticleApplied and environmental microbiology2025

Sugar-inducible promoters for manipulation of core metabolic pathways in the thermophilic acetogen

Benjamin Zeldes, Sabina Mittelstedt, Christoph Baum, Adilia Shakirova, Anja Poehlein, Rolf Daniel, Mirko Basen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Benjamin ZeldesMicrobiology, Institute of Biological Sciences, University of Rostock, Rostock, Germany.ORCID 0000-0003-2039-2446
Sabina MittelstedtMicrobiology, Institute of Biological Sciences, University of Rostock, Rostock, Germany.
Christoph BaumMicrobiology, Institute of Biological Sciences, University of Rostock, Rostock, Germany.ORCID 0009-0004-9024-0733
Adilia ShakirovaMicrobiology, Institute of Biological Sciences, University of Rostock, Rostock, Germany.
Anja PoehleinGenomic and Applied Microbiology & Göttingen Genomics Laboratory, Georg-August-University, Göttingen, Germany.ORCID 0000-0002-2473-6202
Rolf DanielGenomic and Applied Microbiology & Göttingen Genomics Laboratory, Georg-August-University, Göttingen, Germany.ORCID 0000-0002-8646-7925
Mirko BasenMicrobiology, Institute of Biological Sciences, University of Rostock, Rostock, Germany.ORCID 0000-0002-1001-9245

Funding

Bundesministerium für Bildung und Forschung 031B0857ABundesministerium für Bildung und Forschung 031B0857CDeutsche Forschungsgemeinschaft BA5757/2-1
6 · The paper itself

Abstract

Acetogenic bacteria form an essential part of the global carbon cycle and show promise for green chemicals production thanks to their energy-efficient carbon fixation via the Wood-Ljungdahl pathway. Energy conservation in acetogens is dependent on one of two ion-pumping membrane complexes, Rnf or Ech. While the energetics of Rnf acetogens are relatively well understood, Ech-dependent metabolism remains unclear. Like many Ech acetogens, IMPORTANCE: Acetogenic bacteria are industrially relevant for conversion of synthesis gas (syngas, a mixture of hydrogen, H

Indexed as

Metabolic Networks and PathwaysPromoter Regions, GeneticThermoanaerobacterBacterial ProteinsBacterial Proteinsacetogeninducible promotersmetabolic bottleneckthermophileWood-Ljungdahl pathway

Identifiers

PMID41263561
PMCPMC12724272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.