Evidence map›Paper›PMID 41263480›Full record

ArticleHuman vaccines & immunotherapeutics2025

Neonatal and infant mortality after maternal influenza and pertussis vaccination: Probabilistically linked cohort study.

Mohinder Sarna, Christopher C Blyth, Hannah C Moore, Gavin Pereira, Lisa McHugh, Michael Binks, Karin Lust, Paul Van Buynder, Damien Foo, Ross Andrews and 1 more

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mohinder SarnaWesfarmers Centre for Vaccines and Infectious Diseases, The Kids Research Institute Australia, University of Western Australia, Nedlands, Australia.ORCID 0000-0002-2448-1588
Christopher C BlythWesfarmers Centre for Vaccines and Infectious Diseases, The Kids Research Institute Australia, University of Western Australia, Nedlands, Australia.
Hannah C MooreWesfarmers Centre for Vaccines and Infectious Diseases, The Kids Research Institute Australia, University of Western Australia, Nedlands, Australia.
Gavin PereiraCurtin School of Population Health, Curtin University, Bentley, Australia.
Lisa McHughSchool of Public Health, University of Queensland, Brisbane, Australia.
Michael BinksChild and Maternal Health Division, Menzies School of Health Research, Charles Darwin University, Casuarina, Australia.
Karin LustDepartment of Obstetric Medicine, Royal Brisbane and Women's Hospital, Brisbane, Australia.
Paul Van BuynderSchool of Medicine, Griffith University, Southport, Australia.
Damien FooWesfarmers Centre for Vaccines and Infectious Diseases, The Kids Research Institute Australia, University of Western Australia, Nedlands, Australia.
Ross AndrewsCommunicable Disease Control Branch, Queensland Health, Brisbane, Australia.
Annette K ReganWesfarmers Centre for Vaccines and Infectious Diseases, The Kids Research Institute Australia, University of Western Australia, Nedlands, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maternal influenza and pertussis vaccination is an important strategy to reduce morbidity and mortality in infants. Previous vaccine safety studies have mostly focused on the association between maternal vaccination and fetal death. We conducted a probabilistically linked cohort study of mother-infant pairs in three Australian jurisdictions: Queensland, Northern Territory, and Western Australia, to evaluate the risk of all-cause neonatal and infant mortality associated with seasonal influenza and pertussis maternal vaccination. Vaccination records were obtained from regional immunization databases, and mortality information was obtained from perinatal databases and death registries from 2015 to 2017. Cox proportional hazard models with vaccination as time-varying exposure and weighted by the inverse probability of treatment were used to estimate adjusted hazard ratios (aHR). Among 252,924 mothers and 277,979 liveborn infants, 8,288 (3.0%) infants were exposed

Indexed as

Infant MortalityInfluenza, HumanInfluenza VaccinesPertussis VaccineVaccinationAdultAustraliaCohort StudiesFemaleHumansInfantInfant, NewbornMalePregnancyPregnancy Complications, InfectiousWhooping CoughInfluenza VaccinesPertussis VaccineinfluenzaMaternal vaccinesmortalitypertussisvaccine safety

Identifiers

PMID41263480
PMCPMC12645885

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.