Evidence map›Paper›PMID 41263088›Full record

SynthesisWomen's health (London, England)

Exclusive hysteroscopic approach for the treatment of cesarean scar pregnancy: Systematic review of the literature.

Guglielmo Stabile, Laura Vona, Felice Sorrentino, Andrea Etrusco, Antonio Simone Laganà, Stefania Carlucci, Stefano Restaino, Giuseppe Vizzielli, Luigi Nappi

Abstract readSystematic Review
In one paragraph

Synthesis in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guglielmo StabileDepartment of Medical and Surgical Sciences, Institute of Obstetrics and Gynaecology, University of Foggia, Italy.ORCID 0000-0001-9266-3896
Laura VonaDepartment of Medical and Surgical Sciences, Institute of Obstetrics and Gynaecology, University of Foggia, Italy.
Felice SorrentinoDepartment of Medical and Surgical Sciences, Institute of Obstetrics and Gynaecology, University of Foggia, Italy.ORCID 0000-0003-3993-2895
Andrea EtruscoUnit of Obstetrics and Gynecology, "Paolo Giaccone" Hospital, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Italy.
Antonio Simone LaganàUnit of Obstetrics and Gynecology, "Paolo Giaccone" Hospital, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Italy.ORCID 0000-0003-1543-2802
Stefania CarlucciDepartment of Medical and Surgical Sciences, Institute of Obstetrics and Gynaecology, University of Foggia, Italy.
Stefano RestainoClinic of Obstetrics and Gynecology, "Santa Maria della Misericordia" University Hospital, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.ORCID 0000-0002-7848-0329
Giuseppe VizzielliClinic of Obstetrics and Gynecology, "Santa Maria della Misericordia" University Hospital, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.
Luigi NappiDepartment of Medical and Surgical Sciences, Institute of Obstetrics and Gynaecology, University of Foggia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe increase in cesarean section rates in developed countries over the past decades have led to several direct postoperative complications or long-term effects for subsequent pregnancies like cesarean scar pregnancy (CSP).

objectiveMany therapies have been proposed for CSP treatment; however, there is no consensus on the best practice to adopt. Exclusive hysteroscopic treatment has been reported rarely but with good results. To understand the role, the safety, and effectiveness of this approach, we performed a systematic review of the literature.

designThis study is a systematic review. The literature review was performed according to the Preferred Reporting Items for Systematic Reviews. DATA SOURCES AND

methodsWe searched in PubMed, Scopus, and Google Scholar databases until December 2024, with a combination of keywords: ectopic pregnancy, scar pregnancy, hysteroscopy, and treatment. Case reports of randomized controlled trials, prospective controlled studies, prospective cohort studies, retrospective studies, case series, and case reports were considered eligible.

resultsWe identified 265 manuscripts, but at the end of the screening process, we included a total of 8 manuscripts and 158 patients. We have analyzed for each study the age of the patients, pregnancy history, gestational age, presenting symptoms, Transvaginal ultrasound findings, basal beta human chorionic gonadotropin (beta-hCG), the type of hysteroscope used, complications and their management, and time of beta-hCG negativization.

conclusionThe hysteroscopic method represents a feasible and safe approach to the CSP treatment with good outcomes and reproducible even with high levels of beta-hCG and a gestational sac over the 3 cm. An initial gestational sac visualization with a diagnostic hysteroscope and the successive use of the resectoscope seems to be the most effective and safe method. Further multicentric studies and randomized clinical trials are needed to improve and standardize the technique.

Indexed as

Cesarean SectionCicatrixHysteroscopyPregnancy, EctopicFemaleHumansPregnancycesarean scar pregnancyhysteroscopymanagementsurgical approachtreatment

Identifiers

PMID41263088
PMCPMC12638658

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.