Evidence map›Paper›PMID 41263007›Full record

ArticleFrontiers in surgery2025

Type 3A free anterolateral thigh chimeric flap based on the Zunyi classification for reconstructing diabetic foot wounds.

Tianhua Zhang, Xiangkui Wu, Lingli Jiang, Shun'e Xiao, Hai Li, Wei Chen, Shusen Chang, Bihua Wu, Zairong Wei, Chengliang Deng

Abstract read
In one paragraph

Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Tianhua ZhangDepartment of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Xiangkui WuDepartment of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Lingli JiangDepartment of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Shun'e XiaoDepartment of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Hai LiDepartment of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Wei ChenDepartment of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Shusen ChangDepartment of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Bihua WuDepartment of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Zairong WeiDepartment of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Chengliang DengDepartment of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetic foot wounds (DFWs) often present with multilayered tissue loss involving skin, fascia, muscle, and neurovascular structures, posing substantial reconstructive challenges. The Zunyi Classification provides a function-oriented framework for chimeric anterolateral thigh (ALT) flap design. This study aimed to evaluate the clinical efficacy of the Zunyi Type 3A chimeric ALT flap in the reconstruction of complex DFWs. Methods: A retrospective cohort study was carried out involving 28 patients with Wagner grade 2-4 DFWs who underwent reconstruction using a Zunyi Type 3A chimeric ALT flap between June 2021 and June 2024. All flaps were designed based on a single perforator without skin paddle segmentation. Flap composition was tailored to defect characteristics, incorporating combinations of skin, fascia lata, muscle, and sensory nerve. Primary outcomes included flap survival, complication rate, donor-site morbidity, and long-term functional outcome. Results: Among the 28 patients with Wagner grade 2-4 DFWs, the most common flap composition was skin + fascia lata + muscle (S + F + M), applied in 17 cases (60.7%). This was followed by skin + muscle + sensory nerve (S + M + N) in 6 cases (21.4%) and skin + fascia lata + sensory nerve (S + F + N) in 5 cases (17.9%). Flap survival was excellent, with 96.4% demonstrating complete viability; one case of partial distal necrosis was managed successfully with debridement and skin grafting. No donor-site complications were observed. During a median follow-up of 13 months (range: 3-30), none of the patients had ulcer recurrence, major infection, or limb-threatening events occurred. Most patients regained satisfactory ambulatory function while preserving limb integrity. Conclusions: The Zunyi Type 3A chimeric ALT flap offers a reliable, adaptable solution for limb salvage in patients with advanced DFWs. Its capacity to incorporate multiple tissue types in a single, unsegmented design offers effective coverage, structural support, and long-term durability. These findings support broader clinical application of the Zunyi Classification in personalized reconstructive strategies for complex DFWs.

Indexed as

anterolateral thigh flap (ALT)diabetic foot wounds (DFWs)functional outcomelimb salvagemicrosurgical reconstructionmulti-tissue defectsType 3A chimeric flapZunyi classification

Identifiers

PMID41263007
PMCPMC12623312

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