ArticleCurrent health sciences journal
Clinical and Radiological Spectrum in Cleidocranial Dysplasia: A Case Series.
Article in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Cleidocranial dysplasia (CCD) is an autosomal dominant disorder caused by a mutation in Runt-related transcription factor 2 (RUNX2), primarily affecting bones undergoing intramembranous ossification, characterized by generalized dysplasia of bones and teeth. Affected individuals exhibit short stature, partial or complete absence of clavicles, delayed fontanel closure, open skull sutures, multiple wormian bones. Dental issues include retention of deciduous teeth, delayed eruption of permanent teeth, supernumerary teeth, absence of cellular cementum. Diagnosis is based on clinical & radiographic findings. Early diagnosis enhances treatment and quality of life. This case series presents spectrum of clinical and radiographic findings of four adult CCD patients with varying dysplasia manifestations.
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