ArticleFrontiers in neurology2025
Kazakh ThromboTest for intraoperative thrombosis risk assessment during stent-assisted cerebral aneurysm treatment: a single-center clinical study.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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8 authors.
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Abstract
Background: Stent-assisted endovascular treatment of cerebral aneurysms enhances long-term occlusion rates but carries a risk of thromboembolic complications, often influenced by resistance to antiplatelet therapy. Conventional platelet function tests, such as VerifyNow Methods: We retrospectively analyzed 284 patients who underwent stent-assisted aneurysm treatment at a single neurovascular center in Kazakhstan between 2020 and 2023, all of whom received dual antiplatelet therapy. The Kazakh ThromboTest (KTT) was performed intraoperatively in every case, and preoperative platelet reactivity was assessed using the VerifyNow Results: Stent thrombosis occurred in 10 patients (3.52%), including 8 intraoperative and 2 delayed cases. KTT detected all intraoperative events, enabling immediate management such as conversion to balloon-assisted coiling. Among KTT-negative patients, delayed thrombosis occurred in 2 cases (0.7%). VerifyNow Conclusion: The Kazakh ThromboTest represents a practical and cost-effective intraoperative method with a high negative predictive value for identifying acute thrombotic risk during stent-assisted aneurysm repair. Despite adequate VerifyNow
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