ArticleCureus2025
Rare Combined Small-Cell Lung Carcinoma With Lymph Node Metastasis Exclusive to the Small-Cell Component: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Acute Intestinal Obstruction Caused by Dual-Component Metastasis From Combined Small Cell Lung Cancer: A Rare Case and Literature Review.Clinical case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Combined small-cell lung carcinoma (C-SCLC) is a rare histological subtype characterized by the coexistence of small-cell and non-small-cell components, posing diagnostic and therapeutic challenges due to its heterogeneity and aggressive course. We report the case of a 65-year-old heavy smoker who presented with dyspnea and cough. Imaging revealed a right lower lobe mass, and he underwent pneumonectomy. Pathology showed C-SCLC composed of 70% squamous cell carcinoma and 30% small-cell carcinoma (Ki-67: 60%), with vascular invasion, pleural and bone infiltration, and nodal metastases (pT3N1Mx). Early post-operative recurrence with pleural and osseous metastases was observed, and cisplatin-etoposide chemotherapy was initiated. This case illustrates the poor prognosis of C-SCLC, often undetected on small biopsies due to sampling limitations, and underscores the importance of surgical specimens for accurate diagnosis. Given the absence of standardized treatment protocols, management requires a multidisciplinary and individualized approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.