Evidence map›Paper›PMID 41262675›Full record

ArticleJournal of traditional and complementary medicine2025

Anti-inflammatory and antinociceptive effects of

Maryelen A Souza, Ketelin Kunh, Otávio Sanaiotto, Ana C Provinelli, Mayara Barufke, Monica S Z Schindler, Samara Cristina Mazon, J Vladimir Oliveira, Indiara Brusco, Jaqueline Scapinello and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of traditional and complementary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maryelen A SouzaGraduate Program in Environmental Sciences, Community University of Chapecó Region (Unochapecó), Chapecó, Brazil.
Ketelin KunhSchool of Health Sciences, Community University of Chapecó Region (Unochapeco), Chapecó, Brazil.
Otávio SanaiottoSchool of Health Sciences, Community University of Chapecó Region (Unochapeco), Chapecó, Brazil.
Ana C ProvinelliSchool of Health Sciences, Community University of Chapecó Region (Unochapeco), Chapecó, Brazil.
Mayara BarufkeSchool of Health Sciences, Community University of Chapecó Region (Unochapeco), Chapecó, Brazil.
Monica S Z SchindlerGraduate Program in Environmental Sciences, Community University of Chapecó Region (Unochapecó), Chapecó, Brazil.
Samara Cristina MazonGraduate Program in Environmental Sciences, Community University of Chapecó Region (Unochapecó), Chapecó, Brazil.
J Vladimir OliveiraDepartment of Chemical and Food Engineering, Federal University of Santa Catarina (UFSC), Florianópolis, SC, Brazil.
Indiara BruscoGraduate Program in Environmental Sciences, Community University of Chapecó Region (Unochapecó), Chapecó, Brazil.
Jaqueline ScapinelloGraduate Program in Food Science and Technology - State University of Santa Catarina - UDESC, Pinhalzinho, Brazil.
Jacir Dal MagroGraduate Program in Environmental Sciences, Community University of Chapecó Region (Unochapecó), Chapecó, Brazil.
Liz G MüllerGraduate Program in Environmental Sciences, Community University of Chapecó Region (Unochapecó), Chapecó, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: Experimental procedure: The OAG was obtained by hydrodistillation and its composition was determined by gas chromatography-mass spectrometry. The sesquiterpenes pinocamphone, Results and conclusion: The minimum effective dose of OAG in the formalin test was 1 mg/kg. This dose did not affect the locomotor activity of mice. The OAG decreased the number of leukocytes/mm³ in the peritoneal exudate of mice and reduced paw edema 45 min after the arachidonic acid injection. OAG treatment elicited a reduction in NPSH levels in the paw tissue and increased NPSH levels in mice blood plasma and did not cause mice mortality. The OAG is devoid of acute toxicity and shows anti-inflammatory activity, which can be related to the presence of pinocamphone, guaiol, and

Indexed as

Acute toxicity testAnti-inflammatory agentsAntinociceptive agentsNatural productsVerbenaceae

Identifiers

PMID41262675
PMCPMC12624783

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.