Evidence map›Paper›PMID 41262648›Full record

ArticleRespirology case reports2025

A Case of Relapsing Polychondritis With Severe Obstructive Ventilatory Defect Caused by a Single Flare-Up.

Ryusei Nakagawa, Ayaka Kishimoto, Tomohiro Namiki, Hiroya Sunabe, Toshihide Inui, Hiroaki Ishikawa, Hiroko Watanabe, Yuichi Dai, Tohru Sakamoto

Abstract read
In one paragraph

Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ryusei NakagawaDepartment of Respiratory Medicine Tsukuba Memorial Hospital Ibaraki Japan.
Ayaka KishimotoDepartment of Respiratory Medicine Tsukuba Memorial Hospital Ibaraki Japan.
Tomohiro NamikiDepartment of Respiratory Medicine Tsukuba Memorial Hospital Ibaraki Japan.
Hiroya SunabeDepartment of Respiratory Medicine Tsukuba Memorial Hospital Ibaraki Japan.
Toshihide InuiDepartment of Respiratory Medicine Tsukuba Memorial Hospital Ibaraki Japan.
Hiroaki IshikawaDepartment of Respiratory Medicine Tsukuba Memorial Hospital Ibaraki Japan.
Hiroko WatanabeDepartment of Respiratory Medicine Tsukuba Memorial Hospital Ibaraki Japan.
Yuichi DaiDepartment of Diagnostic Pathology Tsukuba Memorial Hospital Ibaraki Japan.
Tohru SakamotoDepartment of Respiratory Medicine Tsukuba Memorial Hospital Ibaraki Japan.ORCID https://orcid.org/0000-0002-8876-1466

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Relapsing polychondritis (RP) is a rare progressive autoimmune disorder affecting cartilaginous and/or proteoglycan-rich structures. Tracheobronchial involvement is observed in almost half of RP cases and significantly impacts the prognosis. We present a case of RP with a rapidly progressive obstructive ventilatory defect caused by a single flare-up, despite significant improvements in the thickening of the airway walls after starting steroid administration. Although the airway walls appeared normal on computed tomography after starting treatment, tracheobronchial cartilage tissues were considered to have been extensively destroyed by chondritis, leading to tracheobronchomalacia and resulting in dynamic respiratory collapse. Preventing fibrosis of the airway walls caused by recurrent flare-ups will be extremely important to avoid fixed airway stenosis.

Indexed as

obstructive ventilatory defectrelapsing polychondritistracheobronchomalaciatransbronchial biopsy

Identifiers

PMID41262648
PMCPMC12626440

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.