ReviewRSC advances2025
Carbon dots as probes in FLIM:a review of applications and advances in cellular imaging.
Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carbon dots (CDs) have emerged as an exceptional alternative to traditional fluorescent probes for cellular imaging due to their high brightness, photostability, tunable fluorescence emission, and low toxicity. These properties make CDs ideal for applications requiring high sensitivity and minimal phototoxicity. However, their optimal potential is realized when combined with advanced fluorescence imaging techniques like fluorescence lifetime imaging microscopy (FLIM). FLIM provides deep insights into dynamic cellular behaviors by measuring fluorescence lifetimes, offering information that traditional intensity-based methods cannot measure. Thus, this review explores the optical properties and fluorescence mechanisms of CDs. The use of UV-vis absorption and photoluminescence (PL) spectroscopy is also discussed to illustrate the unique behavior of CDs. Their applications in cellular imaging, including organelle visualization and real-time tracking of intracellular processes, are examined. The combination of CDs with FLIM enhances the sensitivity of cellular imaging, enabling label-free, time-resolved measurements of cellular dynamics. This integration allows for precise monitoring of metabolic shifts, molecular interactions, and bacterial detection
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.