ArticleRSC advances2025
Multifunctional N-substituted 2-pyridylbenzothiazole derivatives: singlet oxygen generation, protein binding, and photoactivated anticancer and antibacterial activities.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Nano-encapsulatedRSC advances · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study presents the optical characteristics, and biological characteristics of four N-substituted 2-pyridylbenzothiazole derivatives, namely 6-amino-5-(2-benzothiazolyl)-2-oxo-1-phenyl-1,2-dihydro-3-pyridinecarbonitrile (BTZ-Ph), 6-amino-5-(2-benzothiazolyl)-2-oxo-1-(4-chlorophenyl)-1,2-dihydro-3-pyridinecarbonitrile (BTZ-ClPh), 6-amino-5-(2-benzothiazolyl)-2-oxo-1-(4-methylphenyl)-1,2-dihydro-3-pyridinecarbonitrile (BTZ-MePh), and 6-amino-5-(2-benzothiazolyl)-2-oxo-1-(naphthalen-1-yl)-1,2-dihydro-3-pyridinecarbonitrile (BTZ-Nap). The steady-state absorption and emission properties of the examined compounds were assessed in acetonitrile solutions. The fluorescence quantum yields were determined to be 0.27 (BTZ-Ph), 0.24 (BTZ-ClPh), 0.28 (BTZ-MePh), and 0.25 (BTZ-Nap). The biological studies showed a significant interaction of the examined compounds with bovine serum albumin (BSA), where the binding constant (
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.