Evidence map›Paper›PMID 41262568›Full record

ArticleACS pharmacology & translational science2025

α, δ‑

June-Mo Kim, Yu Jin Choi, Hea Jong Chung, Yun Jo Chung, Tae Hwan Kim, Kyoung-Jin Jang, Chan Mi Lee, Yun Kyeong Kwon, Dong Young Kang, Sang Hyeon Park and 5 more

Abstract read
In one paragraph

Article in ACS pharmacology & translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

June-Mo KimDepartment of Microbiology, Jeonbuk National University Medical School, Jeonju 54907, Republic of Korea.ORCID https://orcid.org/0000-0002-2636-1993
Yu Jin ChoiHonam Regional Center, Korea Basic Science Institute (KBSI), Gwangju 61751, Republic of Korea.
Hea Jong ChungHonam Regional Center, Korea Basic Science Institute (KBSI), Gwangju 61751, Republic of Korea.
Yun Jo ChungCenter for University-wide Research Facilities, Jeonbuk National University Medical School, Jeonju 54907, Republic of Korea.
Tae Hwan KimCollege of Pharmacy, Daegu Catholic University, Gyeongsan 38430, Gyeongbuk, Republic of Korea.
Kyoung-Jin JangDepartment of Integrative Biological Sciences and Industry, College of Life Science, Sejong University, Seoul 05006, Republic of Korea.
Chan Mi LeeDepartment of Integrative Biological Sciences and Industry, College of Life Science, Sejong University, Seoul 05006, Republic of Korea.
Yun Kyeong KwonDepartment of Integrative Biological Sciences and Industry, College of Life Science, Sejong University, Seoul 05006, Republic of Korea.
Dong Young KangDepartment of Pathology, School of Medicine, Institute of Biomedical Science and Technology, Konkuk University, Chungju 27478, Republic of Korea.
Sang Hyeon ParkDepartment of Immunology, School of Medicine, Konkuk University, Seoul 05029, Republic of Korea.
Kyoung Seob SongDepartment of Medical Science, Kosin University College of Medicine, Busan 49104, Republic of Korea.
Hyun Chae LeeDepartment of Medical Science, Kosin University College of Medicine, Busan 49104, Republic of Korea.
Seong Tshool HongDepartment of Microbiology, Jeonbuk National University Medical School, Jeonju 54907, Republic of Korea.
Yeong Min ParkDepartment of Integrative Biological Sciences and Industry, College of Life Science, Sejong University, Seoul 05006, Republic of Korea.ORCID https://orcid.org/0000-0001-9741-6333
Hern Ku LeeDepartment of Immunology, Jeonbuk National University Medical School, Jeonju 54907, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

l-Glutamine (Gln) suppresses inflammation via upregulation of mitogen-activated protein kinase (MAPK) phosphatase (MKP)-1; however, high dosages required may cause serious side effects. Here, we developed a glutaminase-resistant less-hydrolyzable Gln derivative, α, δ-

Indexed as

allosteric modulatorexperimental asthmaGPCRMAPK phosphatase-1α, δ-N-acetyl-glutamine

Identifiers

PMID41262568
PMCPMC12624426

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.