Evidence map›Paper›PMID 41262566›Full record

ArticleACS pharmacology & translational science2025

Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models.

Alicja Urbaniak, Billie Heflin, Eric R Siegel, Drew Seale, Megan R Reed, James S Nix, Eric U Yee, Marta Jędrzejczyk, Greta Klejborowska, Natalia Stępczyńska and 10 more

Abstract read
In one paragraph

Article in ACS pharmacology & translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Alicja UrbaniakDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.ORCID https://orcid.org/0000-0002-0807-1263
Billie HeflinDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.
Eric R SiegelWinthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.
Drew SealeDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.
Megan R ReedDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.
James S NixDepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.
Eric U YeeDepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.
Marta JędrzejczykDepartment of Medical Chemistry, Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznanskiego 8, 61-614 Poznań, Poland.
Greta KlejborowskaDepartment of Medical Chemistry, Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznanskiego 8, 61-614 Poznań, Poland.
Natalia StępczyńskaDepartment of Medical Chemistry, Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznanskiego 8, 61-614 Poznań, Poland.
Adam HuczyńskiDepartment of Medical Chemistry, Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznanskiego 8, 61-614 Poznań, Poland.ORCID https://orcid.org/0000-0003-4770-215X
Bolni M NagaloDepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.
Timothy C ChambersDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.ORCID https://orcid.org/0000-0002-3122-9794
Steven R PostDepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.
Robert L EoffDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.ORCID https://orcid.org/0000-0003-4776-8925
Melanie C MacNicolDepartment of Neuroscience, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.
Amit K TiwariDepartment of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.
Thomas KellyDepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.
Alan J TackettDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.ORCID https://orcid.org/0000-0002-3672-4460
Angus M MacNicolWinthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States of America.

Funding

Expanding Translational Research in ArkansasUL1TR003107 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI JAMES, LAURA P · 2019 to 2023
$21.6M
Supplement for Google cloud build-outR24GM137786 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Alan Tackett · 2020 to 2026
$15.4M
Expanding Translational Science in ArkansasUM1TR004909 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI Laura P James · 2024 to 2026
$11.7M
Control of pituitary cell plasticity through regulated mRNA translationR01HD093461 · NICHD · UNIV OF ARKANSAS FOR MED SCIS · PI CHILDS, GWEN V, MACNICOL, ANGUS M · 2018 to 2022
$3.1M
Institutional Career DevelopmentKL2TR003108 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI ARTHUR, JOHN M., BORSHEIM, ELISABET · 2019 to 2023
$2.3M
CTSA K12 Program at the University of Arkansas for Medical SciencesK12TR004924 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI Jason Eli Farrar, Joshua Kennedy · 2024 to 2026
$2.3M
Molecular mechanisms of pituitary plasticityR01DK139476 · NIDDK · UNIV OF ARKANSAS FOR MED SCIS · PI GWEN V CHILDS, MELANIE C MACNICOL · 2024 to 2026
$1.9M
NCATS NIH HHS K12 TR004924NCATS NIH HHS KL2 TR003108NCATS NIH HHS UL1 TR003107NCATS NIH HHS UM1 TR004909NICHD NIH HHS R01 HD093461NIDDK NIH HHS R01 DK139476NIGMS NIH HHS R24 GM137786
6 · The paper itself

Abstract

Monensin (

Indexed as

anti-metastatic agentsbreast cancerbreast cancer metastasiscancer stem cellsmonensinorganoid models

Identifiers

PMID41262566
PMCPMC12624489

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.