ArticleACG case reports journal2025
Nonreportable Cell-Free DNA Prenatal Screening Test Leads to Colorectal Cancer Diagnosis in the Mother.
Article in ACG case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Cell-free DNA, DNA from the developing placenta, is a noninvasive prenatal screening test to detect common fetal chromosomal abnormalities. Rarely, nonreportable results occur when the test cannot accurately determine the fetus chromosomal status. This can be due to low fetal fraction, insufficient DNA, or multiple aneuploidies, which can suggest maternal malignancy. Workup of occult malignancy in pregnancy is challenging. Most malignancies reported to date have been lymphomas. We describe the case of a pregnant patient without cancer risk factors who, following a nonreportable Cell-free DNA test, presented with abdominal pain and intermittent blood per rectum and was ultimately diagnosed with metastatic colon cancer.
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