ArticleCardiovascular therapeutics2025
Risk Factors and Regression of Coronary Aneurysms in Infants With Kawasaki Disease.
Article in Cardiovascular therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: The purpose of this study is to analyze clinical characteristics of patients with Kawasaki disease (KD) aged below 1 year and identify risk factors for coronary aneurysm (CA) and its associated prognosis. Methods: A retrospective study enrolling infants (under 1 year of age) with KD admitted to a children's hospital between January 1, 2012, and August 30, 2024, was conducted. Patients were divided into two groups based on CA presence. Clinical records, including demographics, clinical manifestations, treatments, laboratory parameters, and cardiac ultrasound examination, were collected and analyzed. Results: Of 381 infants with KD, 96 developed CA. Male sex (adjusted odds ratio [aOR] = 1.982, Conclusions: CA incidence was higher in infants with KD and was associated with male sex, fever duration, days of initial IVIG, and higher CRP. The ability and time of regression depend on the size of the CA; however, giant CA in infant patients has a greater tendency to regress than those in older patients with KD.
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