ArticleSage open pediatrics
Predictive Value of Mean Platelet Volume and Other CBC Indices for Thrombocytopenia in Pediatric Dengue Fever: A Prospective Observational Study.
Article in Sage open pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
Introduction: Dengue fever is a major pediatric health challenge, with thrombocytopenia as a key severity marker. Objectives: To assess the predictive value of mean platelet volume, MPV-to-platelet ratio, and other complete blood count (CBC) indices for severe thrombocytopenia in pediatric dengue. Methods: This prospective observational study enrolled 127 children (1 month-15 years) with confirmed dengue at Hue Central Hospital, Vietnam (January 2023-July 2025). CBC parameters were measured on illness days 3 and 6. Severe thrombocytopenia was defined as platelet count <50 000/µL. Results: Severe thrombocytopenia occurred in 15.7% of patients. Day 3 MPV/PLT ratio was the strongest predictor (median 0.10 vs 0.05, Conclusion: MPV/PLT is a simple, early marker for identifying high-risk children with dengue.
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