ArticleOpen forum infectious diseases2025
Epidemiology of Brain Abscess: A Retrospective Cohort From a Neurosurgical Tertiary Referral Center in England.
Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Insertion of a Postoperative Drain After Surgeries for Intracranial Abscesses or Empyemas-A Single-Center Retrospective Study.Neurology international · 2026Article
- Real-World Data on the Use of Intravenous Fosfomycin for the Treatment of Central Nervous System Infections: a Subgroup Analysis from the FORTRESS Study.Infectious diseases and therapy · 2026Article
- Management of community-acquired brain abscess and intracranial empyema: a survey of UK neurosurgical centres.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Streptococcus anginosus group brain abscesses and subdural empyemas: exploratory compartment-specific phenotypes and discharge outcomes in a single-center retrospective cohort study.BMC infectious diseases · 2026Article
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Authors and funding
11 authors.
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Abstract
Background: Brain abscess is a serious infection with substantial morbidity and mortality. Current data on the etiology, management, and outcomes are limited. This study describes the epidemiology of brain abscess in a large patient cohort. Methods: This is a retrospective, observational study of brain abscess at a tertiary referral center. Patients were selected using hospital coding. Demographic, clinical, neurosurgical, and microbiological data were analyzed. Results: We identified 174 patients with brain abscess admitted between 2012 and 2023 (32 pediatric, 142 adults, 66.7% male). Subdural empyema and parenchymal abscess were the most common abscess types in the pediatric and adult cohorts, respectively. A microbiological diagnosis was made in 74.1% of cases. Conclusions: Our data reinforce the importance of early diagnosis and multidisciplinary management, particularly in older patients. Molecular diagnostics, including 16S rRNA gene PCR, may play an increasing role in guiding treatment in the future.
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