Evidence map›Paper›PMID 41262313›Full record

ArticleInternational journal of nanomedicine2025

Multimodal Imaging-Guided Tumor Microenvironment-Responsive Nanoplatform for Synergistic Therapy of Pancreatic Cancer.

Na Li, Haifeng Hu, Yuqi Li, Silong Li, Guangyue Shi, Xiaoyang Yu, Liguo Hao

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Na Li *Department of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, Heilongjiang, 161006, People's Republic of China.
Haifeng Hu *Department of Imaging Medicine and Nuclear Medicine, School of Clinical Medicine, Jiamusi University, Jiamusi, Heilongjiang, 154002, People's Republic of China.
Yuqi LiMedical Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, Heilongjiang, 161006, People's Republic of China.
Silong LiMedical Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, Heilongjiang, 161006, People's Republic of China.ORCID 0009-0008-8663-2266
Guangyue ShiDepartment of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, Heilongjiang, 161006, People's Republic of China.
Xiaoyang YuDepartment of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, Heilongjiang, 161006, People's Republic of China.
Liguo HaoDepartment of Molecular Imaging, School of Medical Technology, Qiqihar Medical University, Qiqihar, Heilongjiang, 161006, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Chemotherapy remains an effective treatment for pancreatic cancer. However, the limitations of single-modal therapies and the absence of imaging-based monitoring during treatment pose challenges for real-time optimization of drug delivery, resulting in suboptimal therapeutic outcomes. Methods: This study aims to design and develop a novel nanoparticle drug delivery system, HMP-ICG&DOX, which incorporates indocyanine green (ICG) as an FDA-approved near-infrared photothermal agent and doxorubicin (DOX) as a commonly used chemotherapeutic drug. The modification with NH Results: Experimental results demonstrate that HMP-ICG&DOX nanoparticles possess excellent biocompatibility, antitumor activity, controlled drug release, and multimodal imaging tracking abilities. Conclusion: In conclusion, the HMP-ICG&DOX nanoparticles designed in this study offer promising applications in the diagnosis and treatment of pancreatic cancer.

Indexed as

Multimodal ImagingNanoparticlesPancreatic NeoplasmsTumor MicroenvironmentAnimalsAntineoplastic AgentsCell Line, TumorDoxorubicinDrug Delivery SystemsDrug LiberationHumansIndocyanine GreenMagnetic Resonance ImagingMiceOptical ImagingAntineoplastic AgentsDoxorubicinIndocyanine Greenadriamycinhollow manganese dioxideindocyanine greenmagnetic resonance imagingpancreatic cancer

Identifiers

PMID41262313
PMCPMC12626041

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.