ArticleClinical case reports2025
Sjögren's Syndrome With Distal Renal Tubular Acidosis and Hypokalemic Myopathy in Pregnancy: A Rare Case.
Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Recurrent Hypokalemic Paralysis as the Initial Presentation of Primary Sjögren's Syndrome.Cureus · 2026Article
- Sjögren's Disease-Associated Renal Tubular Acidosis: An Integrated Immuno-Tubular Model of Tubular Dysfunction.International journal of medical sciences · 2026Review
- Distal Renal Tubular Acidosis in Pregnancy: A Case Report and Systematic Literature Review.European journal of case reports in internal medicine · 2026Article
- Sjögren's Syndrome With Distal Renal Tubular Acidosis and Hypokalemic Myopathy in Pregnancy: A Rare Case.Clinical case reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sjogren's syndrome may rarely present with distal renal tubular acidosis (dRTA), causing severe hypokalemia and myopathy. A 27-year-old primigravida at 15 weeks gestation presented with progressive proximal weakness and myalgia. Labs showed hypokalemia (1.76 mmol/L), hyperchloremic metabolic acidosis, and elevated creatine phosphokinase; urinary pH was 7.0. Anti-SSA/Ro and anti-SSB/La antibodies and a positive Schirmer's test confirmed primary Sjogren's syndrome. Although 16%-67% of Sjogren's syndrome patients present with renal involvement, hypokalemic myopathy due to dRTA in association with Sjogren's syndrome in pregnancy is a very rare presentation. Electromyography showed myopathic changes. Pregnancy likely worsened the electrolyte imbalance. This case highlights the need to consider autoimmune causes in pregnant patients with unexplained hypokalemia and weakness for timely diagnosis and management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.