Evidence map›Paper›PMID 41262223›Full record

ReviewTherapeutics and clinical risk management2025

A Review Vancomycin Role in Gram Positive Biofilm-Associated Infections: Challenges and Emerging Solutions.

Ohood S Alharbi, Khulud A Alhazmi, Malaz Gazzaz, Sarah Almuhayya, Faye A Aldehalan, Asim T Sharif, Bayan Redwan, Mohannad A Alzain, Wafaa Alhazmi, Hala Altarawneh and 14 more

Abstract readReview
In one paragraph

Review in Therapeutics and clinical risk management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Ohood S AlharbiDepartment of Microbiology and Parasitology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.ORCID 0000-0002-8720-5054
Khulud A AlhazmiDepartment of Microbiology and Parasitology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.ORCID 0009-0001-3980-1177
Malaz GazzazPharmaceutical Practices Department, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Sarah AlmuhayyaDepartment of Clinical Laboratory Science, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Faye A AldehalanDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.ORCID 0000-0001-8553-1174
Asim T SharifDepartment of Medical Education, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID 0009-0003-7882-4085
Bayan RedwanDepartment of Medical Education, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Mohannad A AlzainDepartment of Family Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Wafaa AlhazmiDepartment of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID 0000-0001-5322-0953
Hala AltarawnehDepartment of Microbiology and Pathology, Faculty of Medicine, Mutah University, Al-Karak, 61710, Jordan.
Hassan Ahmad Hasan AlfreahatDepartment of Microbiology and Pathology, Faculty of Medicine, Mutah University, Al-Karak, 61710, Jordan.ORCID 0009-0001-7997-921X
Sulaiman Bani Abdel-RahmanDepartment of Microbiology and Pathology, Faculty of Medicine, Mutah University, Al-Karak, 61710, Jordan.
Waiel S HalabiDepartment of Optometry, Faculty of Applied Medical Sciences, University of Jeddah, Jeddah, 23218, Saudi Arabia.ORCID 0000-0002-6198-5566
Rawan AltalhiDepartment of Biological Sciences, College of Science, University of Jeddah, Jeddah, 23445, Saudi Arabia.
Bandar Hasan SalehDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.ORCID 0000-0002-3205-2986
Nabeel Hussain AlhussainyDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Abdulaziz AlsaediDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Hatoon A NiyaziDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Hanouf A NiyaziDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Noha A JumaDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Manal A ZubairDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Mona AlqarniDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Noof HelmiDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Karem IbrahemDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.ORCID 0009-0005-9473-3591

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofilm-associated infections pose a significant challenge in clinical settings due to their increased resistance to antibiotics and evasion of host immune responses. These infections are responsible for a large proportion of chronic and recurrent infections, leading to prolonged hospital stays, increased healthcare costs, and elevated morbidity and mortality rates. Vancomycin, a glycopeptide antibiotic, has long been a cornerstone in the treatment of infections caused by Gram-positive bacteria, particularly methicillin-resistant

Indexed as

biofilm-associated infectionscombination therapydrug delivery systemsvancomycin resistance

Identifiers

PMID41262223
PMCPMC12626027

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.