Evidence map›Paper›PMID 41262215›Full record

ArticleFrontiers in pharmacology2025

Case Report: Carbonic anhydrase inhibitor brinzolamide dramatically improved the morphology and also function of a patient with RS1 mutation.

Yue Ren, Shu Liu, Jia Rong, Di Wang, Miao Diao, Yaqi Zhang, Shimiao Tian, Mingxin Shang, Chuqiao Song, Yan Guan and 2 more

Abstract readCase Reports
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yue Ren *Shenyang He Eye Specialist Hospital, Shenyang, China.
Shu Liu *Shenyang He Eye Specialist Hospital, Shenyang, China.
Jia Rong *Shenyang He Eye Specialist Hospital, Shenyang, China.
Di WangShenyang He Eye Specialist Hospital, Shenyang, China.
Miao DiaoShenyang He Eye Specialist Hospital, Shenyang, China.
Yaqi ZhangShenyang He Eye Specialist Hospital, Shenyang, China.
Shimiao TianShenyang He Eye Specialist Hospital, Shenyang, China.
Mingxin ShangShenyang He Eye Specialist Hospital, Shenyang, China.
Chuqiao SongShenyang He Eye Specialist Hospital, Shenyang, China.
Yan GuanShenyang He Eye Specialist Hospital, Shenyang, China.
Zhuoshi WangShenyang He Eye Specialist Hospital, Shenyang, China.
Jijing PangShenyang He Eye Specialist Hospital, Shenyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

X-linked retinoschisis (XLRS) is an inherited retinal disease caused by mutations in the

Indexed as

carbonic anhydrase inhibitorfoveal thicknessretinoschisisRS1 geneX-linked

Identifiers

PMID41262215
PMCPMC12623332

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.