ArticleAmerican heart journal plus : cardiology research and practice2025
Woven solutions for tissue engineering: Next-generation heart valves from fiber to function.
Article in American heart journal plus : cardiology research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Bioinspired functional materials for biomedical applications.Frontiers in bioengineering and biotechnology · 2026Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Study objective: Cardiovascular diseases remain one of the leading causes of morbidity and mortality worldwide, yet the availability of durable, patient-specific heart valve replacements is still limited. The aim is to utilize a biomimetic, textile-based design to mimic natural tissues, thereby creating customizable solutions with improved mechanical properties and scalable production for cardiovascular applications. Design: By leveraging advanced 3D weaving techniques, the feasibility of manufacturing anatomically adaptable and mechanically robust textile valves is demonstrated. CAD-based design workflows and functional materials such as shape memory Nitinol wires are part of this technology. The integration of form-defining geometries, multilayer structures and functional surface treatments is enabled through tailored binding design and machine adaptations. Main outcome and results: A textile-based heart valve implant was developed using advanced 3D weaving, CAD modelling and patient-specific imaging. Integrated leaflets and an annular ring were formed directly during weaving using mold inserts and multilayer structures, eliminating post-processing. Polyester and Nitinol materials provided mechanical stability and shape-memory functionality. Simulation models and SPH analysis validated pressure behaviour and deformation under physiological conditions. Functional zones with tailored stiffness, sealing and mobility were realized through binding variation and Jacquard control. A reproducible digital workflow, from CT segmentation to weaving on modified looms, enabled scalable production of anatomically accurate, functionally optimized heart valve prostheses. Mechanical evaluations reveal favourable performance in comparison to conventional valve designs. Conclusion: These findings highlight the potential of fiber and textile technology as a scalable, customizable clinically relevant platform for heart valve tissue engineering and future biomedical applications.
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Registered trials
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