ArticleNeurophotonics2026
Tone disruptions in Mandarin post-stroke aphasia: an fNIRS study on Broca's area using the auditory oddball paradigm.
Article in Neurophotonics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- fNIRS reveals comparable reductions in cortical hyperconnectivity following once-daily and twice-daily rTMS in poststroke aphasia.Biomedical optics express · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Significance: Tone processing is essential in tonal languages such as Mandarin. Understanding how post-stroke aphasia (PSA) affects tone perception can guide targeted rehabilitation, especially in linguistically unique populations. Aim: We aimed to explore the neural mechanisms of tone perception in Mandarin-speaking PSA patients and examine how brain network reorganization supports or hinders phonological processing. Approach: Using functional near-infrared spectroscopy (fNIRS) and a tone-based auditory oddball paradigm, we compared cortical activation and functional connectivity (FC) patterns between PSA patients and healthy controls. Results: Patients with PSA showed reduced/reversed hemodynamic responses in the left Broca's area but increased FC with the right motor cortex. Despite this local hyperconnectivity, overall FC was lower in patients than in controls, especially among highly connected links ( Conclusions: The findings highlight altered auditory-motor network dynamics in PSA, with Broca's area playing a central role in tone-based phonological processing. These results support the potential of fNIRS for clinical assessment and underscore the importance of accounting for network-level changes in aphasia rehabilitation strategies for tonal languages.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.