ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- GWA Study Identifies Two Positive Regulators of Mycotoxin Fumonisin B1 Tolerance in Arabidopsis.Genes · 2026Article
- Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Rhizoctonia solani, a globally distributed phytopathogen, causes banded leaf and sheath blight (BLSB) in maize and sheath blight in rice, severely threatening crop productivity. Here, this work identifies ZmRRS1 (Resistance to Rhizoctonia solani 1), which encodes maize malate dehydrogenase, as a key positive regulator of BLSB resistance in the field through a genome-wide association study. ZmRRS1 knockout lines exhibit increased susceptibility to BLSB, whereas overexpression of ZmRRS1 and its homologs confer enhanced resistance to R. solani in both maize and rice. Using heterozygote inbred families (HIF), this work uncovers that the presence and absence of a 831-bp transposable element (TE) element is the causal polymorphism that determines the differential expression pattern of the two ZmRRS1 alleles in response to R. solani. Furthermore, the absence of the TE increases the binding of the ZmWRKY44 transcription factor to the W-box motif in the promoter of ZmRRS1, thereby enhancing BLSB resistance. Transcriptomic analysis reveals that ZmRRS1 potentiates reactive oxygen species (ROS)-mediated immunity against BLSB. Notably, the overexpression of ZmRRS1 does not incur agronomic penalties under normal growth conditions. Collectively, this work identifies ZmRRS1 as a positive regulator of BLSB resistance, offering valuable genetic resources for breeding BLSB-resistant maize and rice varieties.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.