Evidence map›Paper›PMID 41262009›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

CD27 and ICOS as Targets of PD-1/PD-L1 Signaling to Regulate Resident Memory CD8

Yuanyuan Chen, Zhenzhen Wang, Liqiang Song, Qianqian Chen, Hang Zhang, Tao Pan, Jianli Pan, Sheng Zhao, Ting Shang, Hong'en Xu and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. CD27 and ICOS as Targets of PD-1/PD-L1 Signaling to Regulate Resident Memory CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yuanyuan ChenDepartment of Pulmonary and Critical Care Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Zhenzhen WangCardiovascular Center, Department of Ultrasound Medicine, Affiliated People's Hospital, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou, 310014, China.
Liqiang SongDepartment of Pulmonary and Critical Care Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Qianqian ChenDepartment of Pulmonary and Critical Care Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Hang ZhangDepartment of Pulmonary and Critical Care Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Tao PanDepartment of Pulmonary and Critical Care Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Jianli PanDepartment of Special Need, Xi'an Children's Hospital, Xi'an, 710032, China.
Sheng ZhaoState Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, 710032, China.
Ting ShangDepartment of Pulmonary and Critical Care Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Hong'en XuCancer Center, Department of Radiation Oncology, Affiliated People's Hospital, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou, 310014, China.
Xing LvDepartment of Pulmonary and Critical Care Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Jing LiDepartment of Pulmonary and Critical Care Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Fei KangDepartment of Nuclear Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Yongzhan NieState Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, 710032, China.
Feng ZhaoDepartment of Pulmonary and Critical Care Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Lei ShiCancer Center, Department of Radiation Oncology, Affiliated People's Hospital, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou, 310014, China.
Zheng WangDepartment of Pulmonary and Critical Care Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.ORCID https://orcid.org/0009-0003-9638-9195

Funding

National Natural Science Foundation of China 82122033National Natural Science Foundation of China 82270017National Natural Science Foundation of China 82470004Natural Science Foundation of Shanxi Province 2022JQ-858Xi'an Science and Technology Planning Project 22YXYJ0099Zhejiang Provincial People's Hospital Scientific Research Fund Project C-2021-QDJJ08Zhejiang Provincial People's Hospital Scientific Research Fund Project C-2021-QDJJ09Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents A-2023-CXRC12
6 · The paper itself

Abstract

Tissue-resident memory CD8

Indexed as

B7-H1 AntigenCD8-Positive T-LymphocytesImmunologic MemoryInducible T-Cell Co-Stimulator ProteinProgrammed Cell Death 1 ReceptorTumor Necrosis Factor Receptor Superfamily, Member 7AnimalsFemaleHumansLungMiceMice, Inbred C57BLOrthomyxoviridae InfectionsSignal TransductionB7-H1 AntigenIcos protein, mouseInducible T-Cell Co-Stimulator ProteinPdcd1 protein, mouseProgrammed Cell Death 1 ReceptorTumor Necrosis Factor Receptor Superfamily, Member 7costimulatory signalingfibrotic sequelaeinfluenzaPD‐1/PD‐L1resident memory T cells

Identifiers

PMID41262009
PMCPMC12866844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.