Evidence map›Paper›PMID 41261943›Full record

ArticleJournal of the science of food and agriculture2026

Comparative analysis of pomological and phytochemical characteristics in white- and red-fleshed pitaya (Hylocereus spp.), with molecular docking insights into key bioactive compounds.

Kerem Mertoglu, Annik Fischer, Sina Zargarchi, Melekber Sulusoglu Durul, Magdalena Köpsel, Erdi Can Aytar, Ibrahim Bulduk, Barıs Kaki, Tuba Esatbeyoglu

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the science of food and agriculture, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kerem MertogluDepartment of Horticulture, Faculty of Agriculture, Uşak University, Uşak, Türkiye.ORCID https://orcid.org/0000-0002-0490-9073
Annik FischerDepartment of Molecular Food Chemistry and Food Development, Institute of Food and One Health, Gottfried Wilhelm Leibniz University Hannover, Hannover, Germany.
Sina ZargarchiDepartment of Molecular Food Chemistry and Food Development, Institute of Food and One Health, Gottfried Wilhelm Leibniz University Hannover, Hannover, Germany.
Melekber Sulusoglu DurulDepartment of Horticulture, Faculty of Agriculture, Kocaeli University, Kocaeli, Türkiye.
Magdalena KöpselDepartment of Molecular Food Chemistry and Food Development, Institute of Food and One Health, Gottfried Wilhelm Leibniz University Hannover, Hannover, Germany.
Erdi Can AytarDepartment of Horticulture, Faculty of Agriculture, Uşak University, Uşak, Türkiye.
Ibrahim BuldukDepartment of Chemical Engineering, Afyon Kocatepe University, Afyon, Türkiye.
Barıs KakiDepartment of Animal Science, Faculty of Agriculture, Uşak University, Uşak, Türkiye.
Tuba EsatbeyogluDepartment of Molecular Food Chemistry and Food Development, Institute of Food and One Health, Gottfried Wilhelm Leibniz University Hannover, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCacti, including pitaya (Hylocereus spp.), are rich in antioxidants that will undoubtedly gain importance under ongoing climate change as water resources decline. Yet the molecular basis linking composition to antioxidant function remains incompletely defined. We compared white-fleshed H. undatus and red-fleshed H. polyrhizus across physicochemical traits, integrating correlation, principal component analysis, and molecular docking to a human iron-regulatory protein (IRP1).

resultsWhite-fleshed fruits were larger and heavier (length 103.4 mm; width 60.2 mm; weight 204.7 g) than red-fleshed (71.9 mm; 54.5 mm; 126.3 g). Conversely, red-fleshed fruits showed higher total soluble solids (13.47 vs. 9.60 °Brix), total phenolics (379.7 vs. 183.0 mg L

conclusionFindings support species-specific use, with red-fleshed H. polyrhizus serving as a nutrient-dense source of antioxidant compounds, while white-fleshed H. undatus offers advantageous pomological traits. Integrating compositional profiling with multivariate analysis and docking provides mechanistic context and practical implications for breeding, climate-resilient cultivation, and industrial applications. © 2025 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

CactaceaePhytochemicalsPlant ExtractsAntioxidantsFlavonoidsFruitHumansMolecular Docking SimulationPhenolsPlant ProteinsAntioxidantsFlavonoidsPhenolsPhytochemicalsPlant ExtractsPlant Proteinsantioxidant activityin silicomultivariate analysisorganic acidsphenolics

Identifiers

PMID41261943
PMCPMC12872244

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.