Evidence map›Paper›PMID 41261820›Full record

SynthesisActa oncologica (Stockholm, Sweden)2025

The effects of upper versus lower extremity resistance training in patients with breast cancer: a systematic review.

Hacer Oncu, Ceyhun Topcuoglu, Ebru Calık, Melda Saglam, Nacıye Vardar Yaglı

Abstract readComparative StudySystematic Review
In one paragraph

Synthesis in Acta oncologica (Stockholm, Sweden), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hacer OncuDepartment of Cardiorespiratory Physiotherapy and Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey. haceroncu1997@gmail.com.ORCID 0000-0001-8677-0302
Ceyhun TopcuogluDepartment of Cardiorespiratory Physiotherapy and Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey.
Ebru CalıkDepartment of Cardiorespiratory Physiotherapy and Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey.ORCID 0000-0001-5215-5125
Melda SaglamDepartment of Cardiorespiratory Physiotherapy and Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey.ORCID 0000-0001-5323-1943
Nacıye Vardar YaglıDepartment of Cardiorespiratory Physiotherapy and Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey.ORCID 0000-0003-0218-140X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this systematic review was to analyze the effects of upper, lower and upper-lower extremity combined resistance training (RT) in breast cancer survivors.

methodsA systematic literature search was performed using ClinicalTrials.gov, Cochrane Library, PubMed, Scopus, EBSCO, and Web of Science databases. Randomized controlled trials published between 1970 and April 30, 2025 comparing upper extremity RT, lower extremity RT and combined upper and lower extremity RT; comparing upper extremity RT and/or lower extremity RT in the experimental group and no RT in the control group or the sham group in the control group were examined.

resultsWe included 16 studies with 1,207 participants. Upper extremity RT training programs reduce shoulder pain, arm disability and improve upper limb muscle strength. Lower extremity RT training programs improve maximum strength, level of physical activity (PA), 6-minute walking test (6MWT) distance, muscle fatigue indicators and maximal voluntary isometric contraction values. Combined upper-lower extremity RT trainings enhance 6MWT distance, muscular strength, walking speed, body image, and reaction time.

interpretationUpper, lower, and combined upper-lower extremity RT programs can be beneficial rehabilitation therapies for breast cancer survivors. As the effects of the type of RT are different from each other, the specific needs of each patient should be considered while designing the ideal RT in breast cancer survivors.

Indexed as

Breast NeoplasmsLower ExtremityResistance TrainingUpper ExtremityCancer SurvivorsFemaleHumansMuscle StrengthRandomized Controlled Trials as Topic

Identifiers

PMID41261820
PMCPMC12645218

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.