ArticleJournal of the American Chemical Society2025
Skeletal Editing by Tip-Induced Chemistry.
Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Xanthene-to-fluorene skeletal editingChemical science · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skeletal editing of cyclic molecules has garnered considerable attention in the context of drug discovery and green chemistry with notable examples in solution-phase synthesis. Here, we extend the scope of skeletal editing to the single-molecule scale. We demonstrate tip-induced oxygen deletion and ring contraction of an oxygen-containing seven-membered ring on bilayer NaCl films to generate molecules containing the perylene skeleton. The products were identified and characterized at the atomic scale by atomic force microscopy and scanning tunneling microscopy. Insights into the reaction mechanisms were obtained by density functional theory calculations. Our work expands the toolbox of tip-induced chemistry for single-molecule synthesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.