ArticleJournal of animal science and biotechnology2025
Prevotella copri alleviates diarrhea in weaning piglets through gut microbiota modulation and arachidonic acid-AHR-NRF2 pathway activation.
Article in Journal of animal science and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Article
- Associations of Breed andMicroorganisms · 2026Article
- Article
- Effects of Alfalfa Fiber Meal on the In Vitro Fermentation Characteristics and Community Structure of the Colonic Microbiota of Sows.Microorganisms · 2026Article
- Article
- Remodeling the gut microbiota: mechanistic insights into probiotic-mediated alleviation of weaning stress in piglets.Frontiers in immunology · 2026Review
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Authors and funding
7 authors.
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Abstract
backgroundDiarrhea remains a major health concern in both young animals and humans. Prevotella spp., a dominant commensal genus in the healthy porcine gut, becomes increasingly abundant following weaning, suggesting a potential role during this critical transitional period. However, its involvement in post-weaning diarrhea remains poorly understood. Here, we aim to elucidate the role and underlying mechanisms of Prevotella in alleviating diarrhea in weaned piglets.
resultsTo model unsanitary housing conditions, piglets were housed in uncleaned pens containing residual fecal matter from previous occupants and exposed to cold stress by maintaining the ambient temperature at 19 °C, below the optimal 28 °C. Under these conditions, piglets were orally administered either a blank medium (CON, n = 10 × 2) or Prevotella copri at 1 × 10
conclusionsThese findings highlight the role of P. copri in maintaining gut homeostasis and provide new insights into microbiota-based interventions for early-life intestinal disorders.
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