Evidence map›Paper›PMID 41261431›Full record

ArticleJournal of nanobiotechnology2025

Inhalable targeted CD8 + T cell nanoparticles loaded ferroptosis inhibitor ferrostatin-1 alleviate acute lung injury.

Chunhua Ma, Zhaocong Yang, Jing Wang, Xuemei Li, Wei Zhou, Tao Li, Liangming Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chunhua Ma *Women and Children's Hospital of Chongqing Medical University, 400016, Chongqing, China.
Zhaocong Yang *Children's Hospital of Nanjing Medical University, Nanjing, 210009, China.
Jing Wang *School of Biology and Food Engineering, Institute of Pharmaceutical Pharmacology Research Center, Suzhou University, 234099, Anhui, Suzhou, China.
Xuemei LiWomen and Children's Hospital of Chongqing Medical University, 400016, Chongqing, China. 112019@hospital.cqmu.edu.cn.
Wei ZhouWomen and Children's Hospital of Chongqing Medical University, 400016, Chongqing, China. dr.zhouwei@163.com.
Tao LiState Key Laboratory of Trauma, Burns and Combined Injury, Shock and Transfusion Research Department of Army Medical Center, Army Medical University, 400042, Chongqing, P. R. China. lt200132@tmmu.edu.cn.
Liangming LiuState Key Laboratory of Trauma, Burns and Combined Injury, Shock and Transfusion Research Department of Army Medical Center, Army Medical University, 400042, Chongqing, P. R. China. lmliu62@tmmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute lung injury (ALI) is a common clinical complication of sepsis and ferroptosis plays an important role in ALI. The aim of this study was to evaluate the effects of CD8 antibodies modified PD-1 engineered CD8

Indexed as

Acute Lung InjuryCD8-Positive T-LymphocytesCyclohexylaminesFerroptosisNanoparticlesPhenylenediaminesAnimalsDisease Models, AnimalLipopolysaccharidesMaleMiceMice, Inbred C57BLPolylactic Acid-Polyglycolic Acid CopolymerProgrammed Cell Death 1 ReceptorCyclohexylaminesferrostatin-1LipopolysaccharidesPhenylenediaminesPolylactic Acid-Polyglycolic Acid CopolymerProgrammed Cell Death 1 ReceptorAcute lung injuryCD8CD8 + T (CTL)FerroptosisPD-1

Identifiers

PMID41261431
PMCPMC12632152

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.