Evidence map›Paper›PMID 41261418›Full record

ArticleBMC oral health2025

Correlation between e-cigarette use and salivary flow rate, pH, and buffering capacity: a cross-sectional pilot study.

May Alsenani, Loulwah Alothman, Jawaher Alsenaidi, Alhanouf Alnowaiser, Maha Aldawsari, Norah Alharbi

Abstract read
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

May AlsenaniDepartment of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia. mayalsenani@gmail.com.
Loulwah AlothmanDepartment of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
Jawaher AlsenaidiResident, Dental University Hospital, KSU, Riyadh, Saudi Arabia.
Alhanouf AlnowaiserResident, Dental University Hospital, KSU, Riyadh, Saudi Arabia.
Maha AldawsariResident, Dental University Hospital, KSU, Riyadh, Saudi Arabia.
Norah AlharbiResident, Dental University Hospital, KSU, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of e-cigarette use has increased rapidly among youth and adults, partly owing to its advertising as a safer smoking cessation aid. In this cross-sectional pilot study, we aimed to explore the effects of e-smoking, including e-cigarette smoking and nonsmoking, on salivary flow rate, pH, buffering capacity, and salivary consistency.

methodsParticipants aged 18–45 years at the Dental University Hospital who were healthy and with no systemic or salivary gland diseases were included. Saliva samples were collected and analysed using the Saliva-Check Buffer test. Twenty e-smokers and nineteen nonsmokers were recruited as the comparison groups.

resultsAll vapers had low resting saliva (χ² = 16.467, p = 0.000), with higher rates of low buffering capacity (36.8% vs. 1.2%, p = 0.000) and acidic pH (92.9% vs. 7.1%, p = 0.000). Vapers also had reduced saliva flow and altered saliva texture (p = 0.000). These findings indicate that vaping is associated with reduced saliva production, decreased buffering capacity, increased oral acidity, and altered saliva texture.

conclusionsThe study results show that e-cigarettes have a direct effect on saliva. Saliva check kits can serve as educational tools in clinics to help dentists advise and educate e-cigarette smokers about the oral health effects of e-smoking.

Indexed as

Electronic Nicotine Delivery SystemsSalivaSalivationVapingAdolescentAdultBuffersCross-Sectional StudiesFemaleHumansHydrogen-Ion ConcentrationMaleMiddle AgedPilot ProjectsSecretory RateYoung AdultBuffers(MeSH): electronic nicotine delivery systemsNicotineOral healthSalivary glandsSalivation

Identifiers

PMID41261418
PMCPMC12632013

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.