Evidence map›Paper›PMID 41261297›Full record

ReviewCurrent allergy and asthma reports2025

Clinical Impact and Management of Antibiotic Allergy in Pregnancy.

Jamie L Waldron

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jamie L WaldronDepartment of Medicine, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, USA. JLWaldron@mgh.harvard.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of this reviewWe review recent literature on impact of antibiotic allergy during pregnancy, and evidence for management in those self-reporting beta-lactam allergy. RECENT

findingsPregnant patients report a high-rate of antibiotic allergy, similar to the general public. Historically, antibiotic allergy evaluation has been reserved for non-pregnant patients, however, growing evidence supports safety and clinical utility for allergy evaluation during pregnancy. Recent studies have supported safety of outpatient skin testing with drug challenge in those with beta-lactam allergy, with most recent findings supportive of direct drug challenge in patients with low-risk allergy phenotypes. Evaluation of allergy label during pregnancy improves first-line antibiotic use of beta-lactam antibiotics. Allergy evaluation during pregnancy is a unique opportunity for allergists to impact clinical outcomes for both maternal and neonatal outcomes. Future studies should focus on standardization of evaluation protocols, improving access to allergy evaluation, and expand knowledge on neonatal clinical outcomes.

Indexed as

Anti-Bacterial Agentsbeta-LactamsDrug HypersensitivityDisease ManagementFemaleHumansPregnancySkin TestsAnti-Bacterial Agentsbeta-LactamsAdverse drug reactionBeta-lactam allergyHypersensitivity reactionObstetricsPenicillin allergyPregnancy

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.