ArticleJournal of neurology2025
The brief repeatable battery of neuropsychological test (BRB-N) version B: update of Italian normative data.
Article in Journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCognitive impairment affects up to 70% of people with multiple sclerosis (PwMS), mainly impacting memory, processing speed and attention. The Brief Repeatable Battery of Neuropsychological Tests (BRB-N) is widely used to monitor these deficits and has two parallel versions, A and B, to minimize practice effects. The Italian norms for version B have been published years ago and may not reflect current demographic trends.
objectivesTo revise and update normative data for the BRB-N version B in the Italian population and to harmonize these procedures with those used for other neuropsychological batteries used in MS.
methodsWe recruited 224 healthy subjects (94 males, 130 females; mean age = 43.34, standard deviation [SD] = 14.41, range: 19-86 years; mean education = 13.89, SD = 4.05, range = 5-23) from two centers (Milan, Florence). Each raw BRB-N version B score was transformed into a scaled-score metric, then regressed on centered age, centered age
resultsNo significant differences were found in age and sex distribution between centers (all p ≥ 0.87), whereas Milan subjects showed a higher education compared to Florence subjects (p < 0.001). Age and education emerged as consistent predictors across nearly all tests, while sex showed only limited influence. Regression analysis provided normative data to calculate demographically adjusted z scores for each BRB-N version B test. Despite differing sample size and composition, regression coefficients mirrored those from BRB-N version A updated normative data.
conclusionsThese updated, regression-based norms for BRB-N version B align with other major MS neuropsychological batteries in Italy, improving cognitive assessment accuracy in clinical and research settings.
Indexed as
Identifiers
41261205What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.