Evidence map›Paper›PMID 41261169›Full record

ArticleNPJ digital medicine2025

Diagnosis of cardiac conditions from 12-lead electrocardiogram through natural language supervision.

Xue Zhou, Tianhui Li, Hiromasa Hayama, Keijiro Nakamura, Shing-Hong Liu, Wenxi Chen, Xin Zhu

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xue ZhouDivision of Information Systems, Graduate School of Computer Science and Engineering, The University of Aizu, Aizuwakamatsu, Japan.
Tianhui LiDivision of Information Systems, Graduate School of Computer Science and Engineering, The University of Aizu, Aizuwakamatsu, Japan.
Hiromasa HayamaDivision of Cardiovascular Medicine, Toho University Ohashi Medical Center, Tokyo, Japan.
Keijiro NakamuraDivision of Cardiovascular Medicine, Toho University Ohashi Medical Center, Tokyo, Japan.
Shing-Hong LiuDepartment of Computer Science and Information Engineering, Chaoyang University of Technology, Taichung, Taiwan.
Wenxi ChenDivision of Information Systems, Graduate School of Computer Science and Engineering, The University of Aizu, Aizuwakamatsu, Japan. wenxi@u-aizu.ac.jp.
Xin ZhuDepartment of AI Technology Development, M&D Data Science Center, Institute of Integrated Research, Institute of Science Tokyo, Tokyo, Japan. zhu.xin@tmd.ac.jp.

Funding

Japan Science and Technology Agency JPMJKB231Japan Society for the Promotion of Science JP21K10287Japan Society for the Promotion of Science JP25K1597The University of Aizu L502
6 · The paper itself

Abstract

Current AI approaches for cardiac diagnosis require condition-specific supervised learning with extensive labeled datasets, leading to fundamental scalability barriers. We developed an ECG-CLIP model, applying contrastive multimodal learning to enable zero-shot cardiac diagnosis from 12-lead ECGs using natural language supervision. Trained on 800,034 ECG-text pairs from MIMIC-IV-ECG, ECG-CLIP evaluated 18 cardiac conditions without condition-specific training. The model achieved superior performance for rhythm abnormalities (AUROC > 0.90) compared to morphological conditions. External validation demonstrated robust AUROC rank consistency (

Identifiers

PMID41261169
PMCPMC12630586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.