Evidence map›Paper›PMID 41261167›Full record

ArticleCommunications chemistry2025

Structural reconstruction of individual filaments in Aβ

Liam D Aubrey, Liisa Lutter, Kate Fennell, Tracey J Purton, Natasha L Ward, Louise C Serpell, Wei-Feng Xue

Abstract read
In one paragraph

Article in Communications chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Neurotrophic Effects ofInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liam D AubreySchool of Natural Sciences, University of Kent, Canterbury, UK.ORCID http://orcid.org/0000-0003-0420-8274
Liisa LutterSchool of Natural Sciences, University of Kent, Canterbury, UK.ORCID http://orcid.org/0000-0001-7613-1953
Kate FennellSussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, UK.ORCID http://orcid.org/0000-0003-4866-5047
Tracey J PurtonSchool of Natural Sciences, University of Kent, Canterbury, UK.
Natasha L WardSchool of Natural Sciences, University of Kent, Canterbury, UK.
Louise C SerpellSussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, UK.ORCID http://orcid.org/0000-0001-9335-7751
Wei-Feng XueSchool of Natural Sciences, University of Kent, Canterbury, UK. W.F.Xue@kent.ac.uk.ORCID http://orcid.org/0000-0002-6504-0404

Funding

RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/S003312/1RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/T008768/1RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/Z516880/1RCUK | Engineering and Physical Sciences Research Council (EPSRC) EP/R513246/1
6 · The paper itself

Abstract

Structural polymorphism has been demonstrated for both in vitro and ex vivo amyloid fibrils associated with disease. The manner in which different filament structures are assembled from common building blocks remains unclear but the assembly environment is likely to be a key determinant. To address this, three-dimensional reconstruction of individual filament structures was conducted from atomic force microscopy images to map the structural polymorphism landscape of Aβ

Identifiers

PMID41261167
PMCPMC12630867

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.