Evidence map›Paper›PMID 41261162›Full record

ArticlePediatric research2026

Advancing the understanding of age-specific phenotypes in childhood-onset takayasu arteritis.

Khaled Saad, Soha A Hussain, Ahmad Roshdy Ahmad, Mohamed Shawky Elfarargy, Amira Elhoufey, Khalid A Alhasan, Mohamad-Hani Temsah, Mostafa M Embaby

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Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Khaled SaadDepartment of Pediatrics, Assiut University, Assiut, Egypt. Khaled.ali@med.au.edu.eg.ORCID http://orcid.org/0000-0002-8473-6116
Soha A HussainDepartment of Pediatrics, Cairo University, Cairo, Egypt.
Ahmad Roshdy AhmadDepartment of Pediatrics, College of Medicine, Jouf University, Sakaka, Saudi Arabia.
Mohamed Shawky ElfarargyDepartment of Pediatrics, College of Medicine, Jouf University, Sakaka, Saudi Arabia.
Amira ElhoufeyDepartment of Community Health Nursing, Alddrab University College, Jazan University, Jazan, Saudi Arabia.
Khalid A AlhasanDepartment of Pediatrics, College of Medicine, King Saud University, Riyadh, 11461, Saudi Arabia.
Mohamad-Hani TemsahDepartment of Pediatrics, College of Medicine, King Saud University, Riyadh, 11461, Saudi Arabia.
Mostafa M EmbabyDepartment of Pediatrics, Assiut University, Assiut, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

impactChildhood-onset Takayasu arteritis (cTAK) is not a uniform disease but exhibits distinct age-specific clinical and vascular phenotypes across developmental stages, from infants to adolescents. These differences necessitate age-tailored diagnostic approaches and therapeutic strategies to improve outcomes and reduce treatment-related morbidity. The concept of "developmental vasculopathy" links vascular involvement patterns to maturational changes in the arterial wall, addressing critical diagnostic challenges in differentiating incomplete Kawasaki disease from cTAK. The progression toward age-stratified management patterns heralds a new era of personalized medicine in cTAK, with precision diagnostics and tailored interventions to improve outcomes for this serious childhood disease.

Indexed as

Takayasu ArteritisAdolescentAge FactorsAge of OnsetChildChild, PreschoolHumansInfantMucocutaneous Lymph Node SyndromePhenotypePrecision Medicine

Identifiers

PMID41261162

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.